Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.95 |
| ▸ | NR1I2 | O75469 | 9/20 | 0.95 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16880323 | 0.97 | RORC (1.00) | RORCNR1I2NR1H3 | |
| SCHEMBL16888206 | 0.96 | RORC (0.97) | RORCNR1I2NR1H3 | |
| SCHEMBL18204942 | 0.88 | RORC (0.78) | RORCNR1I2NR1H3 | |
| SCHEMBL16888318 | 0.88 | RORC (0.78) | RORCNR1I2NR1H3 | |
| SCHEMBL18204929 | 0.87 | RORC (0.76) | RORCNR1I2NR1H3 | |
| Hydrochloric Acid SCHEMBL16876961 | 0.87 | RORC (0.76) | RORCNR1I2NR1H3 | |
| SCHEMBL19129014 | 0.87 | RORC (0.76) | RORCNR1I2NR1H3 | |
| SCHEMBL16888269 | 0.87 | RORC (0.76) | RORCNR1I2NR1H3 | |
| SCHEMBL16891685 | 0.85 | RORC (1.00) | RORCNR1I2 | |
| SCHEMBL16880281 | 0.85 | RORC (1.00) | RORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015103508-A1 | CARBOCYCLIC SULFONE RORγ MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-07-09 | — | — | WO | disclosed |