Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.37 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999880 | 0.82 | MEN1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL19792025 | 0.81 | MAOB (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL16892153 | 0.81 | TEAD4 (0.59) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL8999877 | 0.80 | MEN1 (0.43) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL22693618 | 0.78 | MEN1 (0.50) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL1100004 | 0.78 | MEN1 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL10269468 | 0.77 | FFAR1 (0.43) | ALDH1A1MRGPRX4 | |
| SCHEMBL1100256 | 0.77 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL257852 | 0.76 | SOS1 (0.50) | SMN1; SMN2MEN1KMT2AMAPTHPGD | |
| SCHEMBL257919 | 0.74 | TEAD4 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2ATEAD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | PHARMASCIENCE, INC. (CA) | 2015-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150191473-A1 | PROTEIN KINASE INHIBITORS | TEC, SRC, LCK | ALDH1A1 4521/4885SMN1; SMN2 4706/4885MEN1 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.