Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL257839 | 0.86 | HTR2A (0.44) | SOS1HTR2ASLC6A4PTGS2KCNH2 | |
| SCHEMBL257919 | 0.85 | TEAD4 (0.48) | SOS1MRGPRX4KMT2ALMNAGFER | |
| SCHEMBL28061160 | 0.83 | LTA4H (0.48) | SOS1SLC6A4FFAR4KMT2ALMNA | |
| SCHEMBL15075246 | 0.83 | LTA4H (0.48) | MRGPRX4L3MBTL1ACHESMN1; SMN2MAOB | |
| SCHEMBL257856 | 0.83 | SOS1 (0.55) | SOS1HTR2ASLC6A4SLC1A3SLC1A2 | |
| SCHEMBL12260917 | 0.82 | SOS1 (0.39) | SOS1HTR2ASLC6A4FFAR4MRGPRX4 | |
| SCHEMBL9900485 | 0.80 | SOS1 (0.38) | SOS1HTR2ASLC6A4FFAR4MRGPRX4 | |
| SCHEMBL27301155 | 0.80 | ALDH1A1 (0.58) | MRGPRX4KMT2ALMNAGFERL3MBTL1 | |
| SCHEMBL257824 | 0.80 | KDM4E (0.46) | SOS1HTR2ASLC6A4KCNH2KMT2A | |
| SCHEMBL8234333 | 0.80 | KDM4C (0.39) | SOS1MRGPRX4KMT2ALMNAGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404607-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-2399585-A1 | Boronic acids and esters as inhibitors of fatty acid amide hydrolase | Infinity Pharmaceuticals, Inc. (US) | 2011-12-28 | — | — | EP | disclosed |