Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
| ▸ | CFD | P00746 | 2/20 | 0.39 |
| ▸ | F11 | P03951 | 2/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | TPSB2 | P20231 | 1/20 | 0.38 |
| ▸ | GYS1 | P13807 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892178 | 0.83 | MAOB (0.51) | KMT2ATDP1L3MBTL1 | |
| SCHEMBL16892162 | 0.82 | SPHK2 (0.58) | SPHK2SPHK1SCN3A | |
| SCHEMBL28495610 | 0.78 | SPHK2 (0.44) | SPHK2SPHK1KMT2AL3MBTL1SCN3A | |
| SCHEMBL30705320 | 0.78 | SPHK2 (0.44) | SPHK2SPHK1KMT2AL3MBTL1SCN3A | |
| SCHEMBL16892215 | 0.77 | TDP1 (0.57) | HTR1AKMT2ATDP1L3MBTL1GYS1 | |
| SCHEMBL10522223 | 0.75 | MAOB (0.53) | HTR1AKMT2ATDP1L3MBTL1HPGD | |
| SCHEMBL16892159 | 0.74 | MAOB (0.50) | — | |
| SCHEMBL8843511 | 0.73 | DPP7 (0.59) | KMT2AHPGD | |
| SCHEMBL16892160 | 0.72 | TDP1 (0.56) | HTR1AKMT2ATDP1L3MBTL1MTNR1A | |
| SCHEMBL16892218 | 0.71 | SPHK2 (0.61) | SPHK2SPHK1KMT2ASCN3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101294-A1 | COMPOUNDS WITH ANALGESIC ACTIVITY AND MEDICAL USE THEREOF | 中国人民解放军军事医学科学院毒物药物研究所 | 2015-07-09 | — | — | WO | disclosed |