Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16892159 | 0.92 | MAOB (0.50) | MAOBMAOASCN9A | |
| SCHEMBL16892179 | 0.86 | MAOB (0.44) | MAOBMAOASCN9A | |
| SCHEMBL16892157 | 0.83 | SPHK2 (0.49) | KMT2ATDP1L3MBTL1 | |
| SCHEMBL16892175 | 0.82 | MAOB (0.60) | MAOBMAOASCN9A | |
| SCHEMBL16892177 | 0.82 | MAOB (0.60) | MAOBMAOASCN9A | |
| SCHEMBL16892223 | 0.81 | SCN9A (0.48) | MAOBMAOASCN9A | |
| SCHEMBL28505222 | 0.80 | MAOB (0.52) | MAOBMAOASCN9A | |
| SCHEMBL30705321 | 0.80 | MAOB (0.52) | MAOBMAOASCN9A | |
| SCHEMBL28505223 | 0.80 | MAOB (0.52) | MAOBMAOASCN9A | |
| SCHEMBL28498221 | 0.79 | MAOB (0.50) | MAOBMAOASCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015101294-A1 | COMPOUNDS WITH ANALGESIC ACTIVITY AND MEDICAL USE THEREOF | 中国人民解放军军事医学科学院毒物药物研究所 | 2015-07-09 | — | — | WO | disclosed |