SCHEMBL16892175

SCHEMBL16892175

C[C@H](NCc1cccc(COc2ccc3c(c2)OCO3)c1)C(N)=O

nearest known ligand 0.60

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 0.60
MAOA P21397 5/20 0.60
SCN9A Q15858 2/20 0.60
NPC1 O15118 3/20 0.49
RAB9A P51151 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16892177 1.00 MAOB (0.60) MAOBMAOASCN9ANPC1RAB9A
SCHEMBL16892163 0.90 MAOB (0.57) MAOBMAOASCN9ANPC1RAB9A
SCHEMBL16892155 0.90 MAOB (0.52) MAOBMAOASCN9ANPC1RAB9A
SCHEMBL16892201 0.88 MAOB (0.52) MAOBMAOASCN9ANPC1RAB9A
SCHEMBL16892156 0.87 KDM4E (0.51) MAOBMAOASCN9A
SCHEMBL16892178 0.82 MAOB (0.51) MAOBMAOASCN9A
SCHEMBL8804044 0.82 ALDH1A1 (0.59)
SCHEMBL16892162 0.82 SPHK2 (0.58) MAOBMAOANPC1RAB9A
SCHEMBL16892220 0.81 SCN9A (0.55) MAOBMAOASCN9A
Hydrochloric Acid SCHEMBL8803794 0.81 MEN1 (0.59)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015101294-A1 COMPOUNDS WITH ANALGESIC ACTIVITY AND MEDICAL USE THEREOF 中国人民解放军军事医学科学院毒物药物研究所 2015-07-09 WO disclosed