Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25327935 | 0.69 | — | — | |
| SCHEMBL29799777 | 0.68 | GAA (0.33) | GAASMN1; SMN2 | |
| SCHEMBL24035650 | 0.66 | GAA (0.34) | GAASMN1; SMN2 | |
| SCHEMBL24031578 | 0.66 | GAA (0.34) | GAASMN1; SMN2 | |
| SCHEMBL279496 | 0.62 | — | — | |
| SCHEMBL24031584 | 0.60 | GAA (0.34) | GAASMN1; SMN2 | |
| SCHEMBL17159484 | 0.59 | ALPL (0.30) | — | |
| SCHEMBL169535 | 0.58 | — | — | |
| SCHEMBL20562547 | 0.58 | TGFBR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL276226 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424368-A1 | PYRROLOTRIAZINE COMPOUNDS | Locus Pharmaceuticals, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |