SCHEMBL168925

SCHEMBL168925

C=CC[Si](CC=C)(CC=C)OS(=O)(=O)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10570362 0.76
SCHEMBL2059573 0.75 CA2 (0.30)
SCHEMBL23728334 0.73
SCHEMBL36993 0.71 CA1 (0.30)
SCHEMBL20337339 0.71
SCHEMBL7105867 0.71
SCHEMBL2059582 0.71
SCHEMBL8149462 0.70
SCHEMBL547479 0.68
SCHEMBL5154385 0.68 EPHX1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 563 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111263760-B Method for preparing a compound 奥瑞生物药品公司 2023-06-23 CN claimed
EP-3694853-B1 PROCESS FOR THE PREPARATION OF 6-(2-HYDROXY-2-METHYLPROPOXY)-4-(6-(6-((6-METHOXYPYRIDIN-3-YL)METHYL)-3,6-DIAZABICYCLO[3.1.1]HEPTAN-3-YL)PYRIDIN-3-YL)PYRAZOLO[1,5-A]PYRIDINE-3-CARBONITRILE ARRAY BIOPHARMA INC (US) 2023-05-17 EP claimed
CN-115403748-A Polycaprolactone derivative and preparation method thereof 鑫元素高新材料(深圳)有限公司 2022-11-29 CN claimed
CN-113816978-A Diamine-boronic ester complex and preparation method and application thereof 北京大学 2021-12-21 CN claimed
EP-3830196-A1 SURFACE TREATMENT COMPOSITIONS AND METHODS FUJIFILM Electronic Materials U.S.A, Inc. (US) 2021-06-09 EP claimed
CN-112513192-A Surface treatment composition and method 富士胶片电子材料美国有限公司 2021-03-16 CN claimed
CN-111499783-B Preparation method of polyacrylate with extremely narrow molecular weight distribution 深圳市鑫元素新材料科技有限公司 2021-02-19 CN claimed
EP-3694853-A1 PROCESS FOR THE PREPARATION OF 6-(2-HYDROXY-2-METHYLPROPOXY)-4-(6-(6-((6-METHOXYPYRIDIN-3-YL)METHYL)-3,6-DIAZABICYCLO[3.1.1]HEPTAN-3-YL)PYRIDIN-3-YL)PYRAZOLO[1,5-A]PYRIDINE-3-CARBONITRILE Array BioPharma Inc. (US) 2020-08-19 EP claimed
CN-111499783-A Preparation method of polyacrylate with extremely narrow molecular weight distribution 深圳市鑫元素新材料科技有限公司 2020-08-07 CN claimed
CN-111263760-A Process for the preparation of 6- (2-hydroxy-2-methylpropoxy) -4- (6- (6- ((6-methoxypyridin-3-yl) methyl) -3, 6-diazabicyclo [3.1.1] hept-3-yl) pyridin-3-yl) pyrazolo [1, 5-a ] pyridine-3-carbonitrile 奥瑞生物药品公司 2020-06-09 CN claimed
US-6323339-B1 GLYCOSYLATING SUBSTRATE IN PRESENCE OF LEWIS ACID; PURIFICATION; COMBINATORIAL CHEMISTRY MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2001-11-27 US claimed
EP-1119577-A2 SYNTHESIS OF OLIGOSACCHARIDES, REAGENTS AND METHODS RELATED THERETO MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2001-08-01 EP claimed
WO-2000020428-A9 SYNTHESIS OF OLIGOSACCHARIDES, REAGENTS AND METHODS RELATED THERETO MASSACHUSETTS INST TECHNOLOGY (US) 2000-10-26 WO claimed
WO-2000020428-A2 SYNTHESIS OF OLIGOSACCHARIDES, REAGENTS AND METHODS RELATED THERETO MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-04-13 WO claimed
EP-0473226-B1 Trialkysilyl trifluoromethanesulfonate mediated functionalization of 4-aza-5alpha-androstan-3-one steroids MERCK & CO INC (US) 1996-07-31 EP claimed
US-5426206-A Stereospecific synthesis of aldols THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-06-20 US claimed
EP-0286926-B1 Semi-synthetic rhodomycins, method for their preparation and their use as cytostatics BEHRINGWERKE AG (DE) 1995-01-11 EP claimed
US-5220003-A Process for the synthesis of 2',3'-dideoxynucleosides THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1993-06-15 US claimed
EP-0212859-B1 FUNGICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-09-12 EP claimed
EP-0212859-A2 Fungicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1987-03-04 EP claimed