Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689446 | 0.90 | HDAC1 (0.61) | HDAC1HDAC2 | |
| SCHEMBL5035388 | 0.85 | HDAC1 (0.61) | HDAC1HDAC2 | |
| SCHEMBL1689494 | 0.82 | HDAC1 (0.64) | HDAC1HDAC2 | |
| SCHEMBL2107730 | 0.80 | HDAC1 (0.69) | HDAC1HDAC2 | |
| SCHEMBL3641983 | 0.78 | HDAC1 (1.00) | HDAC1HDAC2 | |
| SCHEMBL8111485 | 0.76 | HDAC1 (0.77) | HDAC1HDAC2 | |
| SCHEMBL5724398 | 0.75 | HDAC1 (1.00) | HDAC1HDAC2 | |
| SCHEMBL1689312 | 0.74 | HDAC2 (0.62) | HDAC1HDAC2 | |
| SCHEMBL3638201 | 0.74 | HDAC1 (1.00) | HDAC1HDAC2 | |
| SCHEMBL3642943 | 0.74 | HDAC1 (0.76) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896395-A2 | MODIFIED MALONATE DERIVATIVES | Merck & Co., Inc. (US) | 2008-03-12 | — | — | EP | claimed |
| WO-2007002248-A2 | MODIFIED MALONATE DERIVATIVES | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | claimed |
| EP-1896395-A2 | MODIFIED MALONATE DERIVATIVES | Merck & Co., Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007002248-A2 | MODIFIED MALONATE DERIVATIVES | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | disclosed |