Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689312 | 0.89 | HDAC2 (0.62) | HDAC1HDAC2 | |
| SCHEMBL1689267 | 0.85 | HDAC1 (0.63) | HDAC1HDAC2 | |
| SCHEMBL5031042 | 0.80 | HDAC1 (0.71) | HDAC1HDAC2 | |
| SCHEMBL1689389 | 0.79 | HDAC1 (0.67) | HDAC1HDAC2 | |
| SCHEMBL5724398 | 0.77 | HDAC1 (1.00) | HDAC1HDAC2 | |
| SCHEMBL1689215 | 0.77 | HDAC2 (0.75) | HDAC1HDAC2 | |
| SCHEMBL5133250 | 0.77 | HDAC1 (0.56) | HDAC1HDAC2 | |
| SCHEMBL5031094 | 0.75 | HDAC2 (0.55) | HDAC1HDAC2 | |
| SCHEMBL4926542 | 0.75 | HDAC1 (0.73) | HDAC1HDAC2 | |
| SCHEMBL1689446 | 0.74 | HDAC1 (0.61) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896395-B1 | MODIFIED MALONATE DERIVATIVES | MERCK SHARP & DOHME (US) | 2015-07-15 | — | — | EP | claimed |
| EP-1896395-A2 | MODIFIED MALONATE DERIVATIVES | Merck & Co., Inc. (US) | 2008-03-12 | — | — | EP | disclosed |
| WO-2007002248-A2 | MODIFIED MALONATE DERIVATIVES | MERCK & CO., INC. (US) | 2007-01-04 | — | — | WO | disclosed |