Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 6/20 | 0.65 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | NPC1 | O15118 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | ACP1 | P24666 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | MITF | O75030 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.58 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CLK1 | P49759 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18213688 | 0.91 | RAB9A (0.77) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL16896937 | 0.87 | CSNK1D (0.69) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL16896899 | 0.86 | CSNK1D (0.67) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL14189668 | 0.86 | CSNK1D (0.77) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL15112849 | 0.80 | CSNK1D (0.70) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL15489027 | 0.79 | CSNK1D (0.69) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL14189669 | 0.79 | RAB9A (0.74) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL14189673 | 0.79 | RAB9A (0.70) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL14189670 | 0.79 | CSNK1D (0.70) | CSNK1DRAB9ANPC1ALDH1A1KMT2A | |
| SCHEMBL17287704 | 0.79 | CSNK1D (1.00) | CSNK1DRAB9ANPC1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944648-B2 | Organic compounds | INTRA-CELLULAR THERAPIES, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944648-B2 | Organic compounds | INTRA-CELLULAR THERAPIES, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-9944648-B2 | Organic compounds | INTRA-CELLULAR THERAPIES, INC. (US) | 2018-04-17 | — | — | US | disclosed |
| US-20170190703-A9 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-07-06 | — | — | US | disclosed |
| US-20170190703-A9 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-07-06 | — | — | US | disclosed |
| US-20170190703-A9 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2017-07-06 | — | — | US | disclosed |
| EP-3091982-A1 | ORGANIC COMPOUNDS | Intra-Cellular Therapies, Inc. (US) | 2016-11-16 | — | — | EP | disclosed |
| US-20160326179-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2016-11-10 | — | — | US | disclosed |
| US-20160326179-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2016-11-10 | — | — | US | disclosed |
| US-20160326179-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2016-11-10 | — | — | US | disclosed |
| WO-2015106158-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
| WO-2015106158-A1 | ORGANIC COMPOUNDS | INTRA-CELLULAR THERAPIES, INC. (US) | 2015-07-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170190703-A9 | ORGANIC COMPOUNDS | PSEN1, CKMT1A; CKMT1B, GSK3A | CSNK1D 20/4885RAB9A 4386/4885NPC1 396/4885 |
| US-20160326179-A1 | ORGANIC COMPOUNDS | PSEN1, CKMT1A; CKMT1B, GSK3A | CSNK1D 20/4885RAB9A 4386/4885NPC1 396/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.