Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 10/20 | 0.70 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | ACP1 | P24666 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15489027 | 0.93 | CSNK1D (0.69) | CSNK1DLMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL20408266 | 0.92 | CSNK1D (0.68) | CSNK1DLMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL25840648 | 0.91 | ROCK2 (0.61) | CSNK1DLMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL18250793 | 0.89 | MAPT (0.81) | CSNK1DLMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL15113372 | 0.89 | CSNK1D (0.81) | CSNK1DMAPTGAASMN1; SMN2NPC1 | |
| SCHEMBL15113374 | 0.89 | GAA (0.64) | CSNK1DLMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL15112847 | 0.88 | CSNK1D (0.72) | CSNK1DLMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL15112843 | 0.88 | CSNK1D (0.71) | CSNK1DLMNAMAPTGAAPOLB | |
| SCHEMBL17410545 | 0.88 | GAA (0.64) | CSNK1DLMNAMAPTGAASMN1; SMN2 | |
| SCHEMBL15112848 | 0.88 | LMNA (0.62) | CSNK1DLMNAMAPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12018280-B2 | Method for freezing aggregates of pluripotent stem cell-derived cardiomyocytes | KYOTO UNIVERSITY (JP) | 2024-06-25 | — | — | US | disclosed |
| US-20200325448-A1 | METHOD FOR FREEZING AGGREGATES OF PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES | KYOTO UNIVERSITY (JP) | 2020-10-15 | — | — | US | disclosed |
| EP-2966166-B1 | PROMOTER OF DIFFERENTIATION OF PLURIPOTENT STEM CELL INTO MYOCARDIUM, WHICH COMPRISES EGF RECEPTOR INHIBITOR | UNIV KYOTO (JP) | 2019-04-03 | — | — | EP | disclosed |
| US-10233426-B2 | Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds | KYOTO UNIVERSITY (JP) | 2019-03-19 | — | — | US | disclosed |
| US-10196609-B2 | Composition for promoting cardiac differentiation of pluripotent stem cell comprising EGFR inhibitor | KYOTO UNIVERSITY (JP) | 2019-02-05 | — | — | US | disclosed |
| EP-3431584-A1 | FREEZING METHOD FOR AGGREGATES OF PLURIPOTENT STEM CELL-DERIVED MYOCARDIAL CELLS | Kyoto University (JP) | 2019-01-23 | — | — | EP | disclosed |
| US-20170152485-A1 | Method for Inducing Cardiac Differentiation of Pluripotent Stem Cell with Low-Molecular Compounds | KYOTO UNIVERSITY (JP) | 2017-06-01 | — | — | US | disclosed |
| US-20170152485-A1 | Method for Inducing Cardiac Differentiation of Pluripotent Stem Cell with Low-Molecular Compounds | KYOTO UNIVERSITY (JP) | 2017-06-01 | — | — | US | disclosed |
| US-9587220-B2 | Method for inducing cardiac differentiation of pluripotent stem cell | KYOTO UNIVERSITY (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9587220-B2 | Method for inducing cardiac differentiation of pluripotent stem cell | KYOTO UNIVERSITY (JP) | 2017-03-07 | — | — | US | disclosed |
| US-9499790-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2016-11-22 | — | — | US | disclosed |
| US-20160002600-A1 | COMPOSITION FOR PROMOTING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL COMPRISING EGFR INHIBITOR | KYOTO UNIVERSITY (JP) | 2016-01-07 | — | — | US | disclosed |
| US-20160002600-A1 | COMPOSITION FOR PROMOTING CARDIAC DIFFERENTIATION OF PLURIPOTENT STEM CELL COMPRISING EGFR INHIBITOR | KYOTO UNIVERSITY (JP) | 2016-01-07 | — | — | US | disclosed |
| US-8658425-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2014-02-25 | — | — | US | disclosed |
| US-8658425-B2 | Method for promoting differentiation of pluripotent stem cells into cardiac muscle cells | KYOTO UNIVERSITY (JP) | 2014-02-25 | — | — | US | disclosed |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | KYOTO UNIVERSITY (JP) | 2013-07-18 | — | — | US | disclosed |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | KYOTO UNIVERSITY (JP) | 2013-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10233426-B2 | Method for inducing cardiac differentiation of pluripotent stem cell with low-molecular compounds | SRC, MYLK2, YES1 | CSNK1D 207/4885LMNA 4321/4885MAPT 3476/4885 |
| US-20200325448-A1 | METHOD FOR FREEZING AGGREGATES OF PLURIPOTENT STEM CELL-DERIVED CARDIOMYOCYTES | TNNI3, MYLK2, TNNT2 | CSNK1D 2247/4885LMNA 262/4885MAPT 695/4885 |
| US-12018280-B2 | Method for freezing aggregates of pluripotent stem cell-derived cardiomyocytes | TNNI3, MYLK2, TNNT2 | CSNK1D 2247/4885LMNA 262/4885MAPT 695/4885 |
| US-20130183753-A1 | METHOD FOR PROMOTING DIFFERENTIATION OF PLURIPOTENT STEM CELLS INTO CARDIAC MUSCLE CELLS | TNNI3, MYLK2, TNNT2 | CSNK1D 1539/4885LMNA 340/4885MAPT 4471/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.