Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16899462 | 0.86 | KDM4E (0.54) | KDM4EALDH1A1GAANOTUMPKM | |
| SCHEMBL16899368 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1GAANOTUMPKM | |
| SCHEMBL16899426 | 0.84 | ALDH1A1 (0.37) | KDM4EALDH1A1GAANOTUMPKM | |
| SCHEMBL16899382 | 0.81 | ALDH1A1 (0.45) | KDM4EALDH1A1GAAPKMABCG2 | |
| SCHEMBL16899332 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1GAAPKMABCG2 | |
| SCHEMBL29090388 | 0.81 | ATR (0.43) | KDM4EALDH1A1GAANOTUMPKM | |
| SCHEMBL16899359 | 0.80 | HTT (0.41) | KDM4EALDH1A1GAAGPR35KMT2A | |
| SCHEMBL16899338 | 0.77 | KDM4E (0.54) | KDM4EALDH1A1GAAPKMABCG2 | |
| SCHEMBL16899328 | 0.76 | OPRK1 (0.41) | KDM4EALDH1A1GAAMAPTKMT2A | |
| SCHEMBL31158029 | 0.75 | KDM4E (0.56) | KDM4EALDH1A1MAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015104677-A1 | HETEROCYCLIC COMPOUNDS AS EZH2 INHIBITORS | Piramal Enterprises Limited (IN) | 2015-07-16 | — | — | WO | disclosed |