Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1689938 | 1.00 | HDAC1 (0.49) | HDAC1HDAC6SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL10253695 | 0.93 | HDAC1 (0.45) | HDAC1HDAC6SMN1; SMN2GAANPSR1 | |
| SCHEMBL4151596 | 0.91 | HDAC1 (0.43) | HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL4151601 | 0.91 | HDAC1 (0.43) | HDAC1HDAC6SMN1; SMN2 | |
| SCHEMBL13968936 | 0.87 | NOTUM (0.42) | HDAC1HDAC6SMN1; SMN2MEN1KMT2A | |
| SCHEMBL12459707 | 0.86 | NOTUM (0.40) | HDAC1HDAC6SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL14683218 | 0.86 | SMN1; SMN2 (0.41) | HDAC1HDAC6SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL15772672 | 0.86 | SMN1; SMN2 (0.41) | HDAC1HDAC6SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL13563960 | 0.86 | SMN1; SMN2 (0.40) | HDAC1HDAC6SMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL12459808 | 0.85 | SMN1; SMN2 (0.39) | HDAC1HDAC6SMN1; SMN2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010220-A1 | SPIROINDOLINEPIPERIDINE DERIVATIVES | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010220-A1 | SPIROINDOLINEPIPERIDINE DERIVATIVES | RECQL, OPRD1, SKP1 | HDAC1 620/4885HDAC6 117/4885SMN1; SMN2 935/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.