Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.35 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.35 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL572705 | 0.84 | CHRM2 (0.41) | WNT1GSK3BDYRK1AHTR4PLA2G10 | |
| SCHEMBL13698802 | 0.84 | SMN1; SMN2 (0.41) | WNT1GSK3BDYRK1AHTR4PLA2G10 | |
| SCHEMBL6217337 | 0.83 | HTR4 (0.41) | WNT1GSK3BDYRK1AHTR4PLA2G10 | |
| SCHEMBL8486056 | 0.83 | SMN1; SMN2 (0.54) | WNT1GSK3BDYRK1ASMN1; SMN2CHRM1 | |
| SCHEMBL3470166 | 0.83 | PLA2G10 (0.41) | WNT1GSK3BDYRK1AHTR4PLA2G10 | |
| SCHEMBL3799622 | 0.83 | PLA2G10 (0.41) | WNT1GSK3BDYRK1AHTR4PLA2G10 | |
| SCHEMBL27147241 | 0.83 | PLA2G10 (0.41) | WNT1GSK3BDYRK1AHTR4PLA2G10 | |
| SCHEMBL14436566 | 0.83 | HSD11B1 (0.40) | WNT1GSK3BDYRK1AHTR4PLA2G10 | |
| SCHEMBL25355009 | 0.82 | PLA2G10 (0.40) | WNT1GSK3BDYRK1AHTR4PLA2G10 | |
| SCHEMBL18173283 | 0.81 | NR1H2 (0.43) | WNT1GSK3BDYRK1AHTR4PLA2G10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2861577-B1 | TERTIARY AMINES, MEDICAMENTS CONTAINING SAID AMINES, USE THEREOF AND PROCESSES FOR THE PREPARATION THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2017-01-04 | — | — | EP | disclosed |
| US-9078909-B2 | Tertiary amines, medicaments containing said amines, use thereof and processes for the preparation thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-14 | — | — | US | disclosed |
| US-9078909-B2 | Tertiary amines, medicaments containing said amines, use thereof and processes for the preparation thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-07-14 | — | — | US | disclosed |