Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.45 |
| ▸ | VDR | P11473 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.44 |
| ▸ | CBFB | Q13951 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996566 | 0.87 | MAPT (0.49) | CYP3A4TSHRRECQLARVDR | |
| SCHEMBL6515933 | 0.85 | KDM4E (0.53) | CYP3A4TSHRRECQLARVDR | |
| SCHEMBL21635494 | 0.85 | CYP3A4 (0.72) | CYP3A4TSHRRECQLIDO1MAPT | |
| SCHEMBL30991860 | 0.84 | CYP3A4 (0.71) | CYP3A4TSHRRECQLIDO1AR | |
| SCHEMBL20612556 | 0.84 | CYP3A4 (0.71) | CYP3A4TSHRRECQLIDO1AR | |
| SCHEMBL29509773 | 0.82 | IDO1 (0.53) | CYP3A4TSHRRECQLIDO1MAPT | |
| SCHEMBL11333572 | 0.80 | SMN1; SMN2 (0.49) | IDO1ARVDRMAPTALDH1A1 | |
| SCHEMBL24791057 | 0.79 | PRSS1 (0.46) | CYP3A4TSHRRECQLIDO1MAPT | |
| SCHEMBL10499439 | 0.78 | CYP3A4 (0.41) | CYP3A4TSHRRECQLARVDR | |
| SCHEMBL15196187 | 0.77 | ALDH1A1 (0.45) | CYP3A4TSHRIDO1ARVDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515192-B1 | Electrophotographic photoconductor, electrophotographic process, electrophotographic apparatus, and process cartridge | RICOH CO LTD (JP) | 2015-07-15 | — | — | EP | disclosed |