Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.39 |
| ▸ | CYTH2 | Q99418 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996566 | 0.83 | MAPT (0.49) | CYP3A4TSHRRECQLMAPTALDH1A1 | |
| SCHEMBL10499458 | 0.81 | PRSS1 (0.39) | PRSS1MAPTALDH1A1KDM4EGAA | |
| SCHEMBL10499067 | 0.80 | HTT (0.39) | CYP3A4TSHRRECQLMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10498922 | 0.79 | HTT (0.38) | CYP3A4TSHRRECQLPRSS1MAPT | |
| SCHEMBL6515933 | 0.78 | KDM4E (0.53) | CYP3A4TSHRRECQLMAPTALDH1A1 | |
| SCHEMBL16900566 | 0.78 | CYP3A4 (0.52) | CYP3A4TSHRRECQLMAPTALDH1A1 | |
| SCHEMBL10499999 | 0.76 | ALDH1A1 (0.58) | MAPTALDH1A1GAALMNAGLA | |
| SCHEMBL7655830 | 0.73 | SMN1; SMN2 (0.44) | TSHRMAPTALDH1A1KDM4EGAA | |
| SCHEMBL20612556 | 0.73 | CYP3A4 (0.71) | CYP3A4TSHRRECQLMAPTALDH1A1 | |
| SCHEMBL30991860 | 0.73 | CYP3A4 (0.71) | CYP3A4TSHRRECQLMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4835180-A | N-(ω-cyanoalkyl)aminophenols and use as inhibitors of lipoxygenase activity | STERLING DRUG INC. (US) | 1989-05-30 | — | — | US | disclosed |
| EP-0262618-A2 | N-(omega)-cyanoalkyl)aminophenols, and their preparation | STERLING DRUG INC. (US) | 1988-04-06 | — | — | EP | disclosed |