SCHEMBL16900745

SCHEMBL16900745

c1ccc(-c2cc3ccc4[nH]c5ccccc5c4c3s2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK4 P11802 9/20 0.47
CCND1 P24385 9/20 0.47
CYP1A1 P04798 1/20 0.44
CYP1B1 Q16678 1/20 0.44
IMPDH2 P12268 1/20 0.42
IMPDH1 P20839 1/20 0.42
GABRP O00591 1/20 0.41
GABRD O14764 1/20 0.41
GABRA1 P14867 1/20 0.41
GABRB1 P18505 1/20 0.41
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
GABRA2 P47869 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
GABRE P78334 1/20 0.41
GABRA6 Q16445 1/20 0.41
GABRG1 Q8N1C3 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2368350 0.77 CYP1A1 (0.57) CYP1A1CYP1B1HPGDALDH1A1KDM4E
SCHEMBL12278524 0.76 CYP1A1 (0.56) CYP1A1CYP1B1HPGDALDH1A1KDM4E
SCHEMBL23555964 0.74 CYP1A1 (0.54) CYP1A1CYP1B1HPGDALDH1A1KDM4E
SCHEMBL14653387 0.73 GABRP (0.49) CDK4CCND1IMPDH2IMPDH1GABRP
SCHEMBL18429728 0.73 CYP1A1 (0.50) CYP1A1CYP1B1HPGDALDH1A1HSD17B10
SCHEMBL16574518 0.73 CYP1A1 (0.53) CYP1A1CYP1B1ALDH1A1KDM4ELMNA
SCHEMBL23264295 0.73 CYP1A1 (0.53) CYP1A1CYP1B1HPGDALDH1A1KDM4E
SCHEMBL23264294 0.73 CYP1A1 (0.53) CYP1A1CYP1B1HPGDALDH1A1KDM4E
SCHEMBL15542345 0.72 ALDH1A1 (0.44) CDK4CCND1IMPDH2IMPDH1GABRP
SCHEMBL11933063 0.72 GABRP (0.58) CDK4CCND1IMPDH2IMPDH1GABRP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2894157-A1 Condensed cyclic compound and organic light-emitting device including the same Samsung Electronics Co., Ltd (KR) 2015-07-15 EP disclosed