SCHEMBL1690100

SCHEMBL1690100

CCCCC(CC)C[Si]1(CC(CC)CCCC)c2ccsc2-c2sccc21

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
GLA P06280 1/20 0.38
HTT P42858 1/20 0.38
ALDH1A1 P00352 7/20 0.35
TDP1 Q9NUW8 1/20 0.35
CYP3A4 P08684 4/20 0.34
CA2 P00918 2/20 0.33
KDM4E B2RXH2 1/20 0.33
TP53 P04637 1/20 0.32
LMNA P02545 2/20 0.31
MAPK1 P28482 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16594689 0.90 TSHR (0.34) TSHRL3MBTL1GLAHTTALDH1A1
SCHEMBL15977985 0.88 GLA (0.32) TSHRL3MBTL1GLAHTT
SCHEMBL30833817 0.87 TSHR (0.34) TSHRL3MBTL1GLAHTTALDH1A1
SCHEMBL15082227 0.83
SCHEMBL16016258 0.81 GLA (0.31) TSHRL3MBTL1GLAHTT
SCHEMBL18213770 0.80
SCHEMBL16285025 0.80
SCHEMBL16285022 0.80
SCHEMBL16594813 0.78 GLA (0.31) TSHRL3MBTL1GLAHTT
SCHEMBL17449274 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133616-A1 CONJUGATED POLYMER NANOPARTICLE BIOSENSORS STREAM BIO LTD (GB) 2025-06-26 WO claimed
US-12433044-B2 Apparatuses for radiation detection including absorber tiles with a semiconductor material or a perovskite material disposed between the absorber tiles and methods of manufacturing the same Siemens Healthineers Ag (DE) 2025-09-30 US disclosed
WO-2025133616-A1 CONJUGATED POLYMER NANOPARTICLE BIOSENSORS STREAM BIO LTD (GB) 2025-06-26 WO disclosed
EP-3474339-B1 X-RAY IMAGE SENSOR WITH ADHESION PROMOTIVE INTERLAYER AND SOFT-SINTERED PEROVSKITE ACTIVE LAYER Siemens Healthineers Ag (DE) 2024-11-06 EP disclosed
EP-3863059-B1 PEROVSKITE DETECTORS WITH ENHANCED ADHESION Siemens Healthineers Ag (DE) 2024-07-31 EP disclosed
EP-4068363-B1 RADIATION DETECTOR WITH BUTTED ABSORBER TILES WITHOUT DEAD AREAS SIEMENS HEALTHCARE GMBH (DE) 2023-06-07 EP disclosed
EP-4180845-A1 RADIATION DETECTOR WITH LASER CUT ABSORBER TILES Siemens Healthcare GmbH (DE) 2023-05-17 EP disclosed
US-20230145517-A1 RADIATION DETECTOR WITH LASER CUT ABSORBER TILES SIEMENS HEALTHCARE GMBH (DE) 2023-05-11 US disclosed
US-11581359-B2 Multiple spectral detectors using structured perovskite SIEMENS HEALTHCARE GMBH (DE) 2023-02-14 US disclosed
US-11573336-B2 Perovskite-based detectors with increased adhesion SIEMENS HEALTHCARE GMBH (DE) 2023-02-07 US disclosed
US-8455606-B2 Photoactive polymers MERCK PATENT GMBH (DE) 2013-06-04 US disclosed
US-8455606-B2 Photoactive polymers MERCK PATENT GMBH (DE) 2013-06-04 US disclosed
WO-2013065836-A1 PROCESS FOR PRODUCING FUSED-RING AROMATIC COMPOUND, AND CONJUGATED POLYMER 三菱化学株式会社 (JP) 2013-05-10 WO disclosed
WO-2012149189-A2 NOVEL PHOTOACTIVE POLYMERS KONARKA TECHNOLOGIES, INC. (US) 2012-11-01 WO disclosed
US-20120085992-A1 Furan Conjugated Polymers Useful for Photovoltaic Applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-04-12 US disclosed
US-20120085992-A1 Furan Conjugated Polymers Useful for Photovoltaic Applications THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-04-12 US disclosed
US-20110204341-A1 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED POLYMERS PLEXTRONICS, INC. 2011-08-25 US disclosed
US-20110114184-A1 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED AND DIKETOPYRROLOPYRROLE-BASED POLYMERS PLEXTRONICS, INC. 2011-05-19 US disclosed
US-20100032018-A1 Novel Photoactive Polymers KONARKA TECHNOLOGIES, INC. (US) 2010-02-11 US disclosed
US-20070246094-A1 TANDEM PHOTOVOLTAIC CELLS KONARKA TECHNOLOGIES, INC. 2007-10-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110114184-A1 ORGANIC ELECTRONIC DEVICES AND POLYMERS, INCLUDING PHOTOVOLTAIC CELLS AND DIKETONE-BASED AND DIKETOPYRROLOPYRROLE-BASED POLYMERS CCNE2, PIN1, TPRKB TSHR 4520/4885L3MBTL1 1283/4885GLA 3453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.