SCHEMBL1690288

SCHEMBL1690288

COc1ncccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30038861 1.00
SCHEMBL3706881 0.86 DRD1 (0.43)
Ethoxycarbonyl Group SCHEMBL28800612 0.82 NFE2L2 (0.46)
SCHEMBL28437467 0.78 HTR1A (0.47)
SCHEMBL11812262 0.78 GAA (0.51)
SCHEMBL9624731 0.78 NFE2L2 (0.44)
SCHEMBL9827479 0.77
SCHEMBL16175533 0.77 NFE2L2 (0.41)
SCHEMBL15924716 0.77 MAPK8 (0.52)
SCHEMBL364773 0.77 ATM (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 184 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109673644-A The method of Fungicidal composition and prevention and treatment harmful fungoid 石原产业株式会社 2019-04-26 CN claimed
CN-108137616-A Antibacterial agents comprising pyrazino [2,3-b ] [1,4] oxazin-3-ones or related ring systems 葛兰素史克知识产权开发有限公司 2018-06-08 CN claimed
CN-102718785-B The preparation method of aromatic ring boric acid ZHEJIANG CHEMPACIFIC CHEMICAL CO., LTD. (CN) 2016-04-27 CN claimed
CN-105246893-A Pyrazolonaphthyridinone derivatives as metap2 inhibitors (methionine aminopeptidase type-2) SANOFI SA 2016-01-13 CN claimed
CN-105073746-A Substituted imidazopyridines as HDM2 inhibitors MERCK SHARP & DOHME 2015-11-18 CN claimed
CN-104910161-A Pyrazolopyrimidine JAK inhibitor compounds and methods GENENTECH INC 2015-09-16 CN claimed
CN-104870445-A NOVEL DIHYDROPYRIMIDINOISOQUINOLINONES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF INFLAMMATORY DISORDERS (GPR84 ANTAGONISTS) GALAPAGOS NV 2015-08-26 CN claimed
CN-104755461-A 6-aminoindole derivatives as TRP channel antagonists HOFFMANN LA ROCHE 2015-07-01 CN claimed
CN-103918661-A Fungicidal composition and method for controlling noxious fungi ISHIHARA SANGYO KAISHA 2014-07-16 CN claimed
CN-103478142-A Bactericide composition and method of controlling plant disease ISHIHARA SANGYO KAISHA 2014-01-01 CN claimed
CN-101199274-B Bactericide composition and method for controlling plant disease ISHIHARA SANGYO KAISHA 2013-03-20 CN claimed
CN-102083317-A Fungicidal compositions and methods for controlling plant diseases ISHIHARA SANGYO KAISHA 2011-06-01 CN claimed
CN-101483999-A Microbicide composition and method for controlling plant disease injury ISHIHARA SANGYO KAISHA (JP) 2009-07-15 CN claimed
CN-1874680-A bactericide composition and method for controlling plant diseases ISHIHARA SANGYO KAISHA (JP) 2006-12-06 CN claimed
US-20260035362-A1 GLP-1R AGONISTS AND USES THEREOF QILU REGOR THERAPEUTICS INC (CN) 2026-02-05 US disclosed
US-12365670-B2 GLP-IR agonists and uses thereof QILU REGOR THERAPEUTICS INC. (CN) 2025-07-22 US disclosed
EP-4511117-A1 HETEROARYL COMPOUNDS FOR THE TREATMENT OF PAIN Vertex Pharmaceuticals Incorporated (US) 2025-02-26 EP disclosed
US-4062853-A FUNGICIDE THE DOW CHEMICAL COMPANY (US) 1977-12-13 US disclosed
US-3992388-A INTERMEDIATE FOR SULFAMYLUREA HYPOGLYCEMIC AGENTS PFIZER INC. (US) 1976-11-16 US disclosed
US-3933830-A FROM 4-(2-PYRIDYLAMIDOETHYL) PYRIDINES REDUCED WITH HYDROGEN AND A NOBLE METAL CATALYST PFIZER INC. (US) 1976-01-20 US disclosed