SCHEMBL16903530

SCHEMBL16903530

C=CC(=O)OCCOc1c(C)cc(C2(c3cc(C)c(OCCOC(=O)C=C)c(C)c3)c3ccccc3-c3cc4ccccc4cc32)cc1C

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.44
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
PDK2 Q15119 15/20 0.33
MAPT P10636 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 2/20 0.30
TP53 P04637 2/20 0.30
TSHR P16473 2/20 0.30
HIF1A Q16665 2/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19650689 0.93 THRB (0.45) THRBESR1ESR2MAPTSMN1; SMN2
SCHEMBL2230807 0.93 THRB (0.48) THRBESR1ESR2PDK2MAPT
SCHEMBL16551559 0.93 THRB (0.48) THRBESR1ESR2PDK2MAPT
SCHEMBL19651947 0.89 THRB (0.42) THRBMAPTSMN1; SMN2ALDH1A1
SCHEMBL16903532 0.88 THRB (0.43) THRBESR1ESR2PDK2ALDH1A1
SCHEMBL16903538 0.87 THRB (0.46) THRBPDK2
SCHEMBL16903525 0.85 THRB (0.54) THRBPDK2MAPTSMN1; SMN2
SCHEMBL24478129 0.83 THRB (0.51) THRBPDK2MAPTSMN1; SMN2ALDH1A1
SCHEMBL16903527 0.83 THRB (0.48) THRBPDK2ALDH1A1
SCHEMBL24477930 0.83 THRB (0.51) THRBPDK2MAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220169766-A1 CURABLE COMPOSITION, CURED SUBSTANCE, OPTICAL MEMBER, AND LENS FUJIFILM CORPORATION (JP) 2022-06-02 US disclosed
US-11230619-B2 Curable composition, cured product, optical member, lens, and method for producing cured product FUJIFILM CORPORATION (JP) 2022-01-25 US disclosed
US-20190233563-A1 CURABLE COMPOSITION, CURED PRODUCT, OPTICAL MEMBER, LENS, AND METHOD FOR PRODUCING CURED PRODUCT FUJIFILM CORPORATION (JP) 2019-08-01 US disclosed
US-9334352-B2 Semi-cured product, cured product and method for producing these, optical component, curable resin composition, and compound FUJIFILM CORPORATION (JP) 2016-05-10 US disclosed
US-9334352-B2 Semi-cured product, cured product and method for producing these, optical component, curable resin composition, and compound FUJIFILM CORPORATION (JP) 2016-05-10 US disclosed
US-20150197592-A1 SEMI-CURED PRODUCT, CURED PRODUCT AND METHOD FOR PRODUCING THESE, OPTICAL COMPONENT, CURABLE RESIN COMPOSITION, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-16 US disclosed
US-20150197592-A1 SEMI-CURED PRODUCT, CURED PRODUCT AND METHOD FOR PRODUCING THESE, OPTICAL COMPONENT, CURABLE RESIN COMPOSITION, AND COMPOUND FUJIFILM CORPORATION (JP) 2015-07-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150197592-A1 SEMI-CURED PRODUCT, CURED PRODUCT AND METHOD FOR PRODUCING THESE, OPTICAL COMPONENT, CURABLE RESIN COMPOSITION, AND COMPOUND RER1, DCXR, PSME4 THRB 3399/4885ESR1 1795/4885ESR2 1601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.