Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPG | Q9Y5X9 | 17/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | LIPC | P11150 | 8/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16907859 | 0.88 | LIPG (0.55) | LIPGALDH1A1MAPTHTTCLK1 | |
| SCHEMBL16907856 | 0.88 | LIPG (0.76) | LIPGLIPC | |
| SCHEMBL16899384 | 0.81 | LIPG (0.57) | LIPGLIPC | |
| SCHEMBL16899468 | 0.79 | LIPG (0.56) | LIPGLIPC | |
| SCHEMBL20603445 | 0.75 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL15464346 | 0.74 | LIPC (0.76) | LIPGLIPC | |
| SCHEMBL18219150 | 0.73 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL20603428 | 0.72 | LIPG (1.00) | LIPGLIPC | |
| SCHEMBL18219149 | 0.72 | LIPG (0.76) | LIPGLIPC | |
| SCHEMBL19709505 | 0.72 | LIPC (0.56) | LIPGLIPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015105749-A1 | SULFONE AMIDE LINKED BENZOTHIAZOLE INHIBITORS OF ENDOTHELIAL LIPASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2015-07-16 | — | — | WO | disclosed |