SCHEMBL16909005

SCHEMBL16909005

CC(C)(C)OC(=O)N1CC(CCCC(=O)O)C1

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR1H2 P55055 1/20 0.51
FAAH O00519 1/20 0.44
NAMPT P43490 1/20 0.43
GPR119 Q8TDV5 7/20 0.40
USP2 O75604 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
ITGB1 P05556 1/20 0.38
ITGA4 P13612 1/20 0.38
KDM4E B2RXH2 1/20 0.38
PKM P14618 1/20 0.38
ITGB3 P05106 1/20 0.38
ITGA2B P08514 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27033217 0.94 NR1H2 (0.49) NR1H2FAAHNAMPTGPR119USP2
SCHEMBL16629053 0.90 NR1H2 (0.54) NR1H2FAAHNAMPTGPR119USP2
SCHEMBL26470694 0.88 NR1H2 (0.51) NR1H2FAAHNAMPTGPR119USP2
SCHEMBL16921334 0.88 NR1H2 (0.51) NR1H2FAAHNAMPTGPR119USP2
SCHEMBL31747505 0.88 NR1H2 (0.51) NR1H2FAAHNAMPTGPR119USP2
SCHEMBL544238 0.86 FAAH (0.58) FAAHGPR119KDM4EPKMITGB3
SCHEMBL28626485 0.86 MEN1 (0.49) NR1H2FAAHGPR119ITGB1ITGA4
SCHEMBL26547585 0.84 GPR119 (0.48) NR1H2FAAHGPR119KDM4EPKM
SCHEMBL15297794 0.84 NR1H2 (0.54) NR1H2FAAHNAMPTGPR119USP2
SCHEMBL7401533 0.84 NR1H2 (0.58) NR1H2FAAHNAMPTGPR119USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025262297-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 DARK BLUE THERAPEUTICS LTD (GB) 2025-12-26 WO disclosed
EP-4667467-A1 PROTAC DEGRADERS OF MLLT1 AND/OR MLLT3 Dark Blue Therapeutics Ltd (GB) 2025-12-24 EP disclosed
US-9636298-B2 Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs METHYLGENE INC (CA) 2017-05-02 US disclosed
US-9636298-B2 Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs METHYLGENE INC (CA) 2017-05-02 US disclosed
US-9636298-B2 Prodrugs of compounds that enhance antifungal activity and compositions of said prodrugs METHYLGENE INC (CA) 2017-05-02 US disclosed
US-20150203517-A1 Prodrugs of Compounds that Enhance Antifungal Activity and Compositions of Said Prodrugs METHYLGENE INC (CA) 2015-07-23 US disclosed
US-20150203517-A1 Prodrugs of Compounds that Enhance Antifungal Activity and Compositions of Said Prodrugs METHYLGENE INC (CA) 2015-07-23 US disclosed
US-20150203517-A1 Prodrugs of Compounds that Enhance Antifungal Activity and Compositions of Said Prodrugs METHYLGENE INC (CA) 2015-07-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150203517-A1 Prodrugs of Compounds that Enhance Antifungal Activity and Compositions of Said Prodrugs HDAC5, HDAC1, HDAC3 NR1H2 2045/4885FAAH 1677/4885NAMPT 24/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.