Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GMNN | O75496 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15813909 | 0.84 | LMNA (0.57) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL5427277 | 0.84 | LMNA (0.57) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL12137165 | 0.83 | LMNA (0.64) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL5085300 | 0.83 | LMNA (0.55) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL21631711 | 0.83 | MEN1 (0.60) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL29137661 | 0.83 | MEN1 (0.60) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL20742884 | 0.82 | LMNA (0.62) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL19923320 | 0.82 | LMNA (0.62) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| Bromide SCHEMBL6143111 | 0.82 | LMNA (0.62) | LMNASMN1; SMN2CYP1A2MEN1KMT2A | |
| SCHEMBL19923321 | 0.82 | LMNA (0.62) | LMNASMN1; SMN2CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3094968-A1 | METABOLIC SCREENING FOR GESTATIONAL DIABETES | The Regents of The University of California (US) | 2016-11-23 | — | — | EP | disclosed |
| WO-2015109116-A1 | METABOLIC SCREENING FOR GESTATIONAL DIABETES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-07-23 | — | — | WO | disclosed |