SCHEMBL5085300

SCHEMBL5085300

C[N+](C)(C)C[C@@H](CC(=O)O)OC(=O)CC(N)C(=O)[O-]

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.55
▸ SMN1; SMN2 Q16637 1/20 0.55
▸ CYP1A2 P05177 4/20 0.55
▸ MEN1 O00255 5/20 0.54
▸ KMT2A Q03164 5/20 0.54
▸ MAPK1 P28482 4/20 0.54
▸ MAPT P10636 4/20 0.54
▸ GMNN O75496 3/20 0.54
▸ NPSR1 Q6W5P4 3/20 0.54
▸ TP53 P04637 3/20 0.54
▸ TSHR P16473 3/20 0.54
▸ HSP90AA1 P07900 2/20 0.54
▸ BLM P54132 2/20 0.54
▸ NR1H4 Q96RI1 2/20 0.54
▸ CYP2C9 P11712 2/20 0.54
▸ HIF1A Q16665 2/20 0.54
▸ CYP2C19 P33261 2/20 0.53
▸ RECQL P46063 1/20 0.53
▸ GLA P06280 1/20 0.52
▸ PMP22 Q01453 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL6637655 0.88 MEN1 (0.65) LMNASMN1; SMN2CYP1A2MEN1KMT2A
Hydrochloric Acid SCHEMBL6635915 0.86 CYP1A2 (0.57) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL5427277 0.83 LMNA (0.57) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL15813909 0.83 LMNA (0.57) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL16915065 0.83 LMNA (0.57) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL12137165 0.79 LMNA (0.64) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL3193491 0.79 LMNA (0.64) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL21631711 0.79 MEN1 (0.60) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL29137661 0.79 MEN1 (0.60) LMNASMN1; SMN2CYP1A2MEN1KMT2A
SCHEMBL19923321 0.78 LMNA (0.62) LMNASMN1; SMN2CYP1A2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240066001-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES SILTI AG (CH) 2024-02-29 — — US claimed
EP-3164125-B1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES NAN GLOBAL LLC (US) 2023-09-06 — — EP claimed
CN-113387836-A Methods and compositions for treating obesity, preventing weight gain, promoting weight loss, or treating or preventing the development of diabetes NAN全球有限责任公司 2021-09-14 — — CN claimed
US-20210186918-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES MOLECULE X LLC 2021-06-24 — — US claimed
EP-3164125-A2 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES Nan Global, LLC (US) 2017-05-10 — — EP claimed
WO-2016004363-A2 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES NAN Global, LLC (US) 2016-01-07 — — WO claimed
US-20160000745-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES MOLECULE X LLC 2016-01-07 — — US claimed
EP-1218001-B1 ULTRAFINE L-CARNITINE, METHODS OF PREPARING THE SAME, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME SIGMA TAU HEALTHSCIENCE SPA (IT) 2008-12-31 — — EP claimed
US-7303765-B2 Ultrafine-L-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same SIGMA-TAU HEALTHSCIENCE S.P.A. (IT) 2007-12-04 — — US claimed
CN-1706814-A Ultrafine-l-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same SIGMA TAU HEALTHSCIENCE SPA (IT) 2005-12-14 — — CN claimed
US-20050124558-A1 Ultrafine-L-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same SIGMA-TAU HEALTHSCIENCE S.P.A. (IT) 2005-06-09 — — US claimed
EP-1218001-A4 ULTRAFINE L-CARNITINE, METHODS OF PREPARING THE SAME, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME SIGMA TAU HEALTHSCIENCE SPA (IT) 2005-05-18 — — EP claimed
CN-1399549-A Ultra-fine L-carnitine, methods of making, compositions containing, and methods of using SIGMA TAU HEALTHSCIENCE SPA (IT) 2003-02-26 — — CN claimed
US-20020111383-A1 Ultrafine L-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same SIGMA-TAU HEALTHSCIENCE S.P.A. (IT) 2002-08-15 — — US claimed
EP-1218001-A1 ULTRAFINE L-CARNITINE, METHODS OF PREPARING THE SAME, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME Sigma-Tau Healthscience S.p.A. (IT) 2002-07-03 — — EP claimed
WO-2001017525-A1 ULTRAFINE L-CARNITINE, METHODS OF PREPARING THE SAME, COMPOSITIONS CONTAINING THE SAME, AND METHODS OF USING THE SAME SIGMA-TAU HEALTHSCUIENCE S.P.A (IT) 2001-03-15 — — WO claimed
US-20240374552-A1 Compositions and Methods for Preventing or Reducing the Risk of Metabolic Syndrome GARCÍA SADA, FERNANDO (MX) 2024-11-14 — — US disclosed
EP-4393486-A1 COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING THE RISK OF METABOLIC SYNDROME García Sada, Fernando (MX) 2024-07-03 — — EP disclosed
CN-1399549-A Ultra-fine L-carnitine, methods of making, compositions containing, and methods of using SIGMA TAU HEALTHSCIENCE SPA (IT) 2003-02-26 — — CN disclosed
US-20020111383-A1 Ultrafine L-carnitine, methods of preparing the same, compositions containing the same, and methods of using the same SIGMA-TAU HEALTHSCIENCE S.P.A. (IT) 2002-08-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210186918-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES GPR119, CPT1B, CPT2 LMNA 521/4885SMN1; SMN2 2914/4885CYP1A2 4593/4885
US-20240066001-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES GPR119, CPT1B, CPT2 LMNA 521/4885SMN1; SMN2 2914/4885CYP1A2 4593/4885
US-20240374552-A1 Compositions and Methods for Preventing or Reducing the Risk of Metabolic Syndrome GPR119, GPR27, PTPN7 LMNA 3008/4885SMN1; SMN2 3031/4885CYP1A2 4523/4885
US-20160000745-A1 METHODS AND COMPOSITIONS FOR TREATING OBESITY, PREVENTING WEIGHT GAIN, PROMOTING WEIGHT LOSS, PROMOTING SLIMMING, OR TREATING OR PREVENTING THE DEVELOPMENT OF DIABETES GPR119, CPT1B, CPT2 LMNA 521/4885SMN1; SMN2 2914/4885CYP1A2 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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