SCHEMBL16915116

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16925772	1.00	AHR (0.56)	AHRF2CFDCYP1A2CDK5
	SCHEMBL16925709	0.91	AHR (0.56)	AHRF2CFDCYP1A2CDK5
	SCHEMBL16925958	0.87	NPC1 (0.52)	AHRF2CFDCYP1A2ALDH1A1
	SCHEMBL16925949	0.87	CYP1A2 (0.43)	AHRF2CFDCYP1A2CDK5
	SCHEMBL17381086	0.87	AHR (0.64)	AHRCYP1A2ALDH1A1GPR3HSD17B10
	SCHEMBL16925955	0.86	KIF11 (0.53)	AHRF2CFDCYP1A2CDK5
	SCHEMBL16925861	0.83	AHR (0.53)	AHRF2CFDCYP1A2CDK5
	SCHEMBL16925834	0.83	AHR (0.58)	AHRF2CFDCYP1A2CDK5
	SCHEMBL29890056	0.80	AHR (0.64)	AHRCYP1A2ALDH1A1GPR3HSD17B10
	SCHEMBL14822627	0.80	CYP1A2 (0.60)	AHRCYP1A2ALDH1A1GPR3HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.