Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16925958 | 0.91 | NPC1 (0.52) | KIF11KMT2AMEN1NPC1POLB | |
| SCHEMBL16925772 | 0.86 | AHR (0.56) | KIF11KMT2AMEN1NPC1AHR | |
| SCHEMBL16915116 | 0.86 | AHR (0.56) | KIF11KMT2AMEN1NPC1AHR | |
| SCHEMBL16925709 | 0.86 | AHR (0.56) | KIF11KMT2AMEN1NPC1POLB | |
| SCHEMBL16925834 | 0.79 | AHR (0.58) | KIF11KMT2AMEN1NPC1POLB | |
| SCHEMBL16925861 | 0.79 | AHR (0.53) | KIF11KMT2AMEN1NPC1POLB | |
| SCHEMBL16802064 | 0.78 | SMN1; SMN2 (0.64) | KMT2AMEN1NPC1MAOAMAOB | |
| SCHEMBL20040375 | 0.78 | KIF11 (0.54) | KIF11KMT2AMEN1NPC1POLB | |
| SCHEMBL19842112 | 0.77 | ALDH2 (0.43) | KIF11KMT2AMEN1NPC1POLB | |
| SCHEMBL21972829 | 0.76 | KIF11 (0.75) | KIF11KMT2AMEN1NPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000694-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-06-19 | — | — | US | disclosed |
| EP-3094703-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-02-07 | — | — | EP | disclosed |
| WO-2015106789-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000694-B2 | Materials for organic electroluminescent devices | OR10J3, EPCAM, L1CAM | KIF11 2539/4885KMT2A 1418/4885MEN1 1226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.