Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.42 |
| ▸ | RXRA | P19793 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 5/20 | 0.41 |
| ▸ | FEN1 | P39748 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31532198 | 1.00 | FFAR4 (0.43) | FFAR4GRIN2BRXRAGRIN1CYP1A2 | |
| SCHEMBL16915422 | 0.83 | KMT2A (0.53) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL16915413 | 0.79 | NPSR1 (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL31532178 | 0.75 | ALOX5AP (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL16915377 | 0.75 | ALOX5AP (0.45) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL18223959 | 0.73 | ADORA1 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL31532189 | 0.73 | ADORA1 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C19L3MBTL1 | |
| SCHEMBL17840231 | 0.73 | GPR3 (0.50) | FFAR4FFAR1 | |
| SCHEMBL9192280 | 0.73 | L3MBTL1 (0.47) | GRIN2BRXRAGRIN1CYP1A2CYP3A4 | |
| SCHEMBL22634082 | 0.72 | FFAR4 (0.46) | FFAR4GRIN2BSCN9ATRPA1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11447476-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2022-09-20 | — | — | US | disclosed |
| US-20200270238-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2020-08-27 | — | — | US | disclosed |
| CN-111574510-A | Pyrimidinyloxybenzene derivatives as herbicides | FMC 公司 | 2020-08-25 | — | — | CN | disclosed |
| CN-105916849-B | Pyrimidinyloxybenzene derivatives as herbicides | FMC公司 | 2020-07-07 | — | — | CN | disclosed |
| US-10654840-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION (US) | 2020-05-19 | — | — | US | disclosed |
| US-20190084972-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2019-03-21 | — | — | US | disclosed |
| EP-3094631-B1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORP (US) | 2019-01-09 | — | — | EP | disclosed |
| US-10131652-B2 | Pyrimidinyloxy benzene derivatives as herbicides | FMC CORPORATION | 2018-11-20 | — | — | US | disclosed |
| EP-3094631-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2016-11-23 | — | — | EP | disclosed |
| US-20160333000-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | FMC CORPORATION | 2016-11-17 | — | — | US | disclosed |
| WO-2015108779-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10131652-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | FFAR4 3561/4885GRIN2B 1671/4885RXRA 965/4885 |
| US-10654840-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | FFAR4 3561/4885GRIN2B 1671/4885RXRA 965/4885 |
| US-20200270238-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | FFAR4 3561/4885GRIN2B 1671/4885RXRA 965/4885 |
| US-20160333000-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | FFAR4 3561/4885GRIN2B 1671/4885RXRA 965/4885 |
| US-11447476-B2 | Pyrimidinyloxy benzene derivatives as herbicides | DDT, NQO2, CBR3 | FFAR4 3561/4885GRIN2B 1671/4885RXRA 965/4885 |
| US-20190084972-A1 | PYRIMIDINYLOXY BENZENE DERIVATIVES AS HERBICIDES | DDT, NQO2, CBR3 | FFAR4 3561/4885GRIN2B 1671/4885RXRA 965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.