SCHEMBL16918812

SCHEMBL16918812

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc(-n4c5ccccc5c5ccc6c(cnn6-c6ccccc6)c54)cc3)n2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR3C1 P04150 2/20 0.41
▸ KDM4E B2RXH2 2/20 0.41
▸ ATM Q13315 1/20 0.41
▸ L3MBTL1 Q9Y468 1/20 0.41
▸ PIK3CA P42336 1/20 0.38
▸ MTOR P42345 1/20 0.38
▸ MAPT P10636 3/20 0.37
▸ TP53 P04637 1/20 0.37
▸ CYP17A1 P05093 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ PGR P06401 1/20 0.36
▸ PTGS2 P35354 1/20 0.36
▸ POLB P06746 1/20 0.36
▸ KMT2A Q03164 1/20 0.36
▸ NPSR1 Q6W5P4 1/20 0.36
▸ HSD17B10 Q99714 1/20 0.36
▸ GRM1 Q13255 3/20 0.36
▸ ALDH1A1 P00352 1/20 0.35
▸ LMNA P02545 1/20 0.35
▸ HTT P42858 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19051899 0.94 NR3C1 (0.40) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL19051619 0.94 NR3C1 (0.40) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL15811174 0.93 NR3C1 (0.45) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL16918822 0.93 NR3C1 (0.41) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL15811222 0.91 KDM4E (0.38) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL19051614 0.91 NR3C1 (0.37) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL19051857 0.91 RAC2 (0.40) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL16425016 0.91 NR3C1 (0.40) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL15811240 0.91 PIK3CA (0.39) NR3C1KDM4EATML3MBTL1PIK3CA
SCHEMBL15811233 0.90 RAC2 (0.38) NR3C1KDM4EATML3MBTL1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 — — US disclosed
US-11678498-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2023-06-13 — — US disclosed
EP-2897185-B1 Organic light-emitting device SAMSUNG DISPLAY CO LTD (KR) 2020-12-16 — — EP disclosed
US-10573822-B2 Organic electroluminescent device DOOSAN CORPORATION (KR) 2020-02-25 — — US disclosed
US-20170294613-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 — — US disclosed
US-20170294613-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2017-10-12 — — US disclosed
US-9543538-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-10 — — US disclosed
US-9543538-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-10 — — US disclosed
US-20160322583-A1 ORGANIC ELECTROLUMINESCENT DEVICE DOOSAN CORPORATION (KR) 2016-11-03 — — US disclosed
US-20160322583-A1 ORGANIC ELECTROLUMINESCENT DEVICE DOOSAN CORPORATION (KR) 2016-11-03 — — US disclosed
US-20150207093-A1 ORGANIC LIGHT-EMITTING DEVICE SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2015-07-23 — — US disclosed
US-20150207093-A1 ORGANIC LIGHT-EMITTING DEVICE SOLUS ADVANCED MATERIALS CO., LTD. (KR) 2015-07-23 — — US disclosed
EP-2897185-A1 Organic light-emitting device Samsung Display Co., Ltd. (KR) 2015-07-22 — — EP disclosed
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