Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 16/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | GALK1 | P51570 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13878189 | 1.00 | PDK2 (0.39) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL15870808 | 0.96 | PDK2 (0.40) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL13878173 | 0.95 | PDK2 (0.38) | PDK2MAPTL3MBTL1PGR | |
| SCHEMBL17678563 | 0.92 | PDK2 (0.39) | PDK2PGR | |
| SCHEMBL24119109 | 0.92 | PDK2 (0.34) | PDK2 | |
| SCHEMBL17153686 | 0.90 | PDK2 (0.40) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL5841679 | 0.90 | PDK2 (0.43) | PDK2MEN1MAPTKMT2AATM | |
| SCHEMBL13914895 | 0.90 | PDK2 (0.36) | PDK2MEN1APAF1NPC1LMNA | |
| SCHEMBL13878163 | 0.90 | PDK2 (0.36) | PDK2PGR | |
| SCHEMBL13725520 | 0.90 | RXRA (0.35) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230058635-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| US-11258018-B2 | Compounds and organic electronic devices | MERCK PATENT GMBH (DE) | 2022-02-22 | — | — | US | disclosed |
| WO-2020108899-A1 | ELECTRONIC DEVICE | MERCK PATENT GMBH (DE) | 2020-06-04 | — | — | WO | disclosed |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2019-11-14 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| US-9768391-B2 | Derivatives of 2-diarylaminofluorene and organic electronic compounds containing them | MERCK PATENT GMBH (DE) | 2017-09-19 | — | — | US | disclosed |
| EP-2875699-B1 | DERIVATES OF 2-DIARYLAMINOFLUOREN AND ORGANIC ELECTRONIC DEVICES COMPRISING THE SAME | MERCK PATENT GMBH (DE) | 2017-02-15 | — | — | EP | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | MERCK PATENT GMBH (DE) | 2015-07-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150207075-A1 | DERIVATIVES OF 2-DIARYLAMINOFLUORENE AND ORGANIC ELECTRONIC COMPOUNDS CONTAINING THEM | DDT, AFF2, CYP2F1 | PDK2 718/4885MEN1 514/4885APAF1 2588/4885 |
| US-20190348605-A1 | COMPOUNDS AND ORGANIC ELECTRONIC DEVICES | ETV6, CYP2C19, AFF2 | PDK2 1406/4885MEN1 292/4885APAF1 3911/4885 |
| US-20170317285-A1 | Compounds and Organic Electronic Devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885MEN1 292/4885APAF1 3911/4885 |
| US-11258018-B2 | Compounds and organic electronic devices | ETV6, CYP2C19, AFF2 | PDK2 1406/4885MEN1 292/4885APAF1 3911/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.