Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18222604 | 0.91 | PIK3C3 (0.86) | PIK3C3 | |
| SCHEMBL16923711 | 0.90 | PIK3C3 (1.00) | PIK3C3 | |
| SCHEMBL16923779 | 0.89 | PIK3C3 (1.00) | PIK3C3 | |
| SCHEMBL16923780 | 0.89 | PIK3C3 (0.80) | PIK3C3 | |
| SCHEMBL16923726 | 0.89 | PIK3C3 (0.93) | PIK3C3 | |
| SCHEMBL18232214 | 0.88 | PIK3C3 (0.85) | PIK3C3 | |
| SCHEMBL18232219 | 0.87 | PIK3C3 (0.77) | PIK3C3 | |
| SCHEMBL16923764 | 0.87 | PIK3C3 (1.00) | PIK3C3 | |
| SCHEMBL20724825 | 0.84 | PIK3C3 (0.74) | PIK3C3 | |
| SCHEMBL16923769 | 0.84 | PIK3C3 (1.00) | PIK3C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202373-B2 | Heteroaryls and uses thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2019-02-12 | — | — | US | disclosed |
| US-20160333007-A1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-11-17 | — | — | US | disclosed |
| US-20160333007-A1 | HETEROARYLS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-11-17 | — | — | US | disclosed |
| WO-2015108881-A1 | HETEROARYLS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-07-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160333007-A1 | HETEROARYLS AND USES THEREOF | VPS35, VPS4B, VPS26B | PIK3C3 981/4885 |
| US-10202373-B2 | Heteroaryls and uses thereof | VPS35, VPS4B, VPS26B | PIK3C3 981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.