Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TLR2 | O60603 | 4/20 | 0.45 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.45 |
| ▸ | MDM4 | O15151 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20435349 | 0.94 | KMT2A (0.52) | KMT2ATLR2TLR1MDM2 | |
| SCHEMBL31010133 | 0.94 | KMT2A (0.52) | KMT2ATLR2TLR1MDM2 | |
| SCHEMBL29400519 | 0.92 | TLR2 (0.51) | KMT2ATLR2TLR1MDM4TP53 | |
| SCHEMBL29531876 | 0.92 | TLR2 (0.54) | KMT2ATLR2TLR1MDM2 | |
| SCHEMBL29521704 | 0.92 | TLR2 (0.51) | KMT2ATLR2TLR1MDM4TP53 | |
| SCHEMBL31493934 | 0.92 | TLR2 (0.51) | KMT2ATLR2TLR1MDM4TP53 | |
| SCHEMBL5312217 | 0.92 | TLR2 (0.51) | KMT2ATLR2TLR1MDM4TP53 | |
| SCHEMBL12852253 | 0.92 | TLR2 (0.51) | KMT2ATLR2TLR1MDM4TP53 | |
| SCHEMBL14770862 | 0.92 | TLR2 (0.44) | KMT2ATLR2MDM4TP53MDM2 | |
| SCHEMBL30546904 | 0.89 | TLR2 (0.48) | KMT2ATLR2TLR1MDM4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015106599-A1 | CONJUGATES AND COMPOSITIONS FOR DRUG DELIVERY | BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) | 2015-07-23 | — | — | WO | disclosed |