SCHEMBL29400519

SCHEMBL29400519

CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)ON1C(=O)CCC1=O

nearest known ligand 0.68

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TLR2 O60603 3/20 0.51
▸ TLR1 Q15399 1/20 0.51
▸ MDM2 Q00987 2/20 0.47
▸ KMT2A Q03164 2/20 0.46
▸ KLK7 P49862 1/20 0.44
▸ KLK5 Q9Y337 1/20 0.44
▸ ACE P12821 1/20 0.42
▸ TDP1 Q9NUW8 1/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ MDM4 O15151 1/20 0.41
▸ TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29521704 1.00 TLR2 (0.51) TLR2TLR1MDM2KMT2AKLK7
SCHEMBL12852253 1.00 TLR2 (0.51) TLR2TLR1MDM2KMT2AKLK7
SCHEMBL31493934 1.00 TLR2 (0.51) TLR2TLR1MDM2KMT2AKLK7
SCHEMBL5312217 1.00 TLR2 (0.51) TLR2TLR1MDM2KMT2AKLK7
SCHEMBL30546904 0.97 TLR2 (0.48) TLR2TLR1MDM2KMT2AKLK7
SCHEMBL12852250 0.97 TLR2 (0.49) TLR2TLR1MDM2KMT2AKLK7
SCHEMBL29531876 0.97 TLR2 (0.54) TLR2TLR1MDM2KMT2AKLK7
SCHEMBL16925663 0.92 KMT2A (0.53) TLR2TLR1MDM2KMT2AMDM4
SCHEMBL19718318 0.89 TLR2 (0.44) TLR2TLR1MDM2KMT2AKLK7
SCHEMBL20435349 0.89 KMT2A (0.52) TLR2TLR1MDM2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113173987-B Method for synthesizing linatide 汉肽生物医药集团有限公司 2022-11-29 — — CN claimed
CN-113135988-B Preparation method of thymosin beta 4 润辉生物技术(威海)有限公司 2022-04-01 — — CN claimed
US-20260061065-A1 ANTIBODY DRUG CONJUGATES NOVARTIS AG (CH) 2026-03-05 — — US disclosed
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF NOVARTIS AG (CH) 2025-12-25 — — US disclosed
US-12377175-B2 Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies CORNELL UNIVERSITY (US) 2025-08-05 — — US disclosed
WO-2025111431-A1 ANTI-CD7 ANTIBODY-DRUG CONJUGATES AND METHODS OF USE THEREOF LES LABORATOIRES SERVIER (FR) 2025-05-30 — — WO disclosed
US-12268759-B2 Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies CORNELL UNIVERSITY (US) 2025-04-08 — — US disclosed
EP-4525928-A1 ANTIBODY DRUG CONJUGATES Novartis AG (CH) 2025-03-26 — — EP disclosed
EP-4525927-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF Novartis AG (CH) 2025-03-26 — — EP disclosed
CN-119630672-A Camptothecin derivative and conjugate thereof, and preparation method and medical application thereof 一线医药(杭州)有限公司 2025-03-14 — — CN disclosed
WO-2025042989-A1 PSMA-BASED ALBUMIN BINDING AGENTS FOR TARGETED RADIONUCLIDE THERAPY OF PROSTATE CANCER THE JOHNS HOPKINS UNIVERSITY (US) 2025-02-27 — — WO disclosed
WO-2023075435-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE 주식회사 베르티스 2023-05-04 — — WO disclosed
US-20230114130-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES COMELL UNIVERSITY (US) 2023-04-13 — — US disclosed
CN-115677827-A Peptide compounds 深圳市健元医药科技有限公司 2023-02-03 — — CN disclosed
CN-113173987-B Method for synthesizing linatide 汉肽生物医药集团有限公司 2022-11-29 — — CN disclosed
WO-2022212958-A1 HETEROBIVALENT AND HOMOBIVALENT AGENTS TARGETING FIBROBLAST ACTIVATION PROTEIN ALPHA AND/OR PROSTATE-SPECIFIC MEMBRANE ANTIGEN THE JOHNS HOPKINS UNIVERSITY (US) 2022-10-06 — — WO disclosed
US-20220283131-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS CO., LTD. (KR) 2022-09-08 — — US disclosed
CN-113135988-B Preparation method of thymosin beta 4 润辉生物技术(威海)有限公司 2022-04-01 — — CN disclosed
US-11285227-B2 Trifunctional constructs with tunablepharmacokinetics useful in imaging and anti-tumor therapies CORNELL UNIVERSITY (US) 2022-03-29 — — US disclosed
WO-2022050529-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE ㈜베르티스 2022-03-10 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11285227-B2 Trifunctional constructs with tunablepharmacokinetics useful in imaging and anti-tumor therapies MC2R, OGFR, GLS TLR2 4118/4885TLR1 3839/4885MDM2 1763/4885
US-20250387504-A1 ANTIBODY-DRUG CONJUGATES OF ANTINEOPLASTIC COMPOUNDS AND METHODS OF USE THEREOF BID, BCL2, MCL1 TLR2 4179/4885TLR1 4298/4885MDM2 384/4885
US-20230114130-A1 TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES VHL, GLS, KRAS TLR2 4003/4885TLR1 3865/4885MDM2 796/4885
US-20260061065-A1 ANTIBODY DRUG CONJUGATES FCGR2A, FCGR3B, BCL3 TLR2 1153/4885TLR1 534/4885MDM2 3219/4885
US-12377175-B2 Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies VHL, GLS, GPER1 TLR2 4148/4885TLR1 4326/4885MDM2 163/4885
US-12268759-B2 Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies VHL, GLS, GPER1 TLR2 4148/4885TLR1 4326/4885MDM2 163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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