Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 3/20 | 0.51 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12852253 | 1.00 | TLR2 (0.51) | TLR2TLR1MDM2KMT2AKLK7 | |
| SCHEMBL31493934 | 1.00 | TLR2 (0.51) | TLR2TLR1MDM2KMT2AKLK7 | |
| SCHEMBL5312217 | 1.00 | TLR2 (0.51) | TLR2TLR1MDM2KMT2AKLK7 | |
| SCHEMBL29400519 | 1.00 | TLR2 (0.51) | TLR2TLR1MDM2KMT2AKLK7 | |
| SCHEMBL30546904 | 0.97 | TLR2 (0.48) | TLR2TLR1MDM2KMT2AKLK7 | |
| SCHEMBL12852250 | 0.97 | TLR2 (0.49) | TLR2TLR1MDM2KMT2AKLK7 | |
| SCHEMBL29531876 | 0.97 | TLR2 (0.54) | TLR2TLR1MDM2KMT2AKLK7 | |
| SCHEMBL16925663 | 0.92 | KMT2A (0.53) | TLR2TLR1MDM2KMT2AMDM4 | |
| SCHEMBL19718318 | 0.89 | TLR2 (0.44) | TLR2TLR1MDM2KMT2AKLK7 | |
| SCHEMBL20435349 | 0.89 | KMT2A (0.52) | TLR2TLR1MDM2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12377175-B2 | Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies | CORNELL UNIVERSITY (US) | 2025-08-05 | — | — | US | disclosed |
| US-20250214985-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2025-07-03 | — | — | US | disclosed |
| US-20250163040-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2025-05-22 | — | — | US | disclosed |
| US-12268759-B2 | Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies | CORNELL UNIVERSITY (US) | 2025-04-08 | — | — | US | disclosed |
| US-12258339-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | CORNELL UNIVERSITY (US) | 2025-03-25 | — | — | US | disclosed |
| US-12103922-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | CORNELL UNIVERSITY (US) | 2024-10-01 | — | — | US | disclosed |
| EP-4326741-A1 | CYCLOPOLYPHOSPHAZENES, RELATED METHODS OF PREPARATION AND METHODS OF USE | University of Saskatchewan (CA) | 2024-02-28 | — | — | EP | disclosed |
| US-20240050599-A1 | TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES | CORNELL UNIVERSITY (US) | 2024-02-15 | — | — | US | disclosed |
| US-20230285603-A1 | TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES | CORNELL UNIVERSITY (US) | 2023-09-14 | — | — | US | disclosed |
| US-20230114130-A1 | TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES | COMELL UNIVERSITY (US) | 2023-04-13 | — | — | US | disclosed |
| WO-2022221959-A1 | CYCLOPOLYPHOSPHAZENES, RELATED METHODS OF PREPARATION AND METHODS OF USE | UNIVERSITY OF SASKATCHEWAN (CA) | 2022-10-27 | — | — | WO | disclosed |
| US-20220274974-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2022-09-01 | — | — | US | disclosed |
| US-20220185803-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2022-06-16 | — | — | US | disclosed |
| US-20220177461-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | CORNELL UNIVERSITY (US) | 2022-06-09 | — | — | US | disclosed |
| US-11285227-B2 | Trifunctional constructs with tunablepharmacokinetics useful in imaging and anti-tumor therapies | CORNELL UNIVERSITY (US) | 2022-03-29 | — | — | US | disclosed |
| US-11279698-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | CORNELL UNIVERSITY (US) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11285227-B2 | Trifunctional constructs with tunablepharmacokinetics useful in imaging and anti-tumor therapies | MC2R, OGFR, GLS | TLR2 4118/4885TLR1 3839/4885MDM2 1763/4885 |
| US-20220185803-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | TLR2 4003/4885TLR1 3231/4885MDM2 3516/4885 |
| US-20220274974-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, KLK3, FOLH1 | TLR2 4143/4885TLR1 3504/4885MDM2 3675/4885 |
| US-20220177461-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | TLR2 4003/4885TLR1 3231/4885MDM2 3516/4885 |
| US-20230114130-A1 | TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES | VHL, GLS, KRAS | TLR2 4003/4885TLR1 3865/4885MDM2 796/4885 |
| US-20230285603-A1 | TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES | VHL, GLS, GPER1 | TLR2 4148/4885TLR1 4326/4885MDM2 163/4885 |
| US-20240050599-A1 | TRIFUNCTIONAL CONSTRUCTS WITH TUNABLE PHARMACOKINETICS USEFUL IN IMAGING AND ANTI-TUMOR THERAPIES | VHL, GLS, GPER1 | TLR2 4148/4885TLR1 4326/4885MDM2 163/4885 |
| US-11279698-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | PSMA1, FOLH1, KLK3 | TLR2 4003/4885TLR1 3231/4885MDM2 3516/4885 |
| US-12377175-B2 | Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies | VHL, GLS, GPER1 | TLR2 4148/4885TLR1 4326/4885MDM2 163/4885 |
| US-20250163040-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | TLR2 4003/4885TLR1 3231/4885MDM2 3516/4885 |
| US-12258339-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | PSMA1, FOLH1, KLK3 | TLR2 4003/4885TLR1 3231/4885MDM2 3516/4885 |
| US-12268759-B2 | Trifunctional constructs with tunable pharmacokinetics useful in imaging and anti-tumor therapies | VHL, GLS, GPER1 | TLR2 4148/4885TLR1 4326/4885MDM2 163/4885 |
| US-12103922-B2 | Macrocyclic complexes of alpha-emitting radionuclides and their use in targeted radiotherapy of cancer | PSMA1, KLK3, FOLH1 | TLR2 4143/4885TLR1 3504/4885MDM2 3675/4885 |
| US-20250214985-A1 | MACROCYCLIC COMPLEXES OF ALPHA-EMITTING RADIONUCLIDES AND THEIR USE IN TARGETED RADIOTHERAPY OF CANCER | PSMA1, FOLH1, KLK3 | TLR2 4003/4885TLR1 3231/4885MDM2 3516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.