SCHEMBL2859340

SCHEMBL2859340

C=C[CH]CCCCCCCCCCCCCC

nearest known ligand 0.62

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.62
ALDH1A1 P00352 1/20 0.46
THRB P10828 1/20 0.44
FAAH O00519 3/20 0.42
TRPV1 Q8NER1 1/20 0.42
DNM1 Q05193 3/20 0.41
EP300 Q09472 1/20 0.38
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1705800 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL169329 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL2871946 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL3078400 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL1114864 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL1076957 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL2869472 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL1395419 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL10980289 1.00 TSHR (0.62) TSHRALDH1A1THRBFAAHTRPV1
SCHEMBL298912 1.00

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4297258-A Non-yellowing paint formulations containing iodo substituted alkynyl urethanes as fungicides ICI AMERICAS INC. (US) 1981-10-27 US claimed
US-4104175-A FREEZE-THAW STABLE MODOKEMI AKTIEBOLAG (SE) 1978-08-01 US claimed
WO-2024109552-A1 MANUFACTURING METHOD FOR LIGHT-EMITTING DEVICE, LIGHT-EMITTING DEVICE, AND ELECTRONIC APPARATUS TCL科技集团股份有限公司 2024-05-30 WO disclosed
WO-2024051766-A1 MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-03-14 WO disclosed
WO-2023165681-A1 RNA LIPID NANOPARTICLES (LNPS) COMPRISING A POLYOXAZOLINE AND/OR POLYOXAZINE POLYMER BioNTech SE (DE) 2023-09-07 WO disclosed
WO-2023166099-A1 RNA LIPID NANOPARTICLES (LNPs) COMPRISING A POLYOXAZOLINE AND/OR POLYOXAZINE POLYMER BioNTech SE (DE) 2023-09-07 WO disclosed
US-10287531-B2 Free-flowing, solid, high active alkyl ether sulfates GALAXY SURFACTANTS LTD. (IN) 2019-05-14 US disclosed
EP-3022279-B1 FREE-FLOWING, SOLID, HIGH ACTIVE ALKYL ETHER SULFATES GALAXY SURFACTANTS LTD (IN) 2019-03-27 EP disclosed
US-20190021998-A1 TOPICAL NANOEMULSION THERAPY FOR WOUNDS THE REGENTS OF THE UNIVERSITY OF MICHIGAN 2019-01-24 US disclosed
EP-3010983-B1 ANTIMICROBIAL INKS AND SEALANTS GROS ROBERT TIMOTHY (GB) 2019-01-16 EP disclosed
CN-109134530-A A kind of pair of hydrophobic based surfactants and preparation method thereof 浙江科峰有机硅有限公司 2019-01-04 CN disclosed
WO-2014202941-A1 ANTIMICROBIAL INKS AND SEALANTS GROS ROBERT TIMOTHY (GB) 2014-12-24 WO disclosed
WO-2012065610-A1 METHOD AND SUBSTRATE WITH A QUAT COATING VESTERGAARD FRANDSEN SA (CH) 2012-05-24 WO disclosed
US-20100099738-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-04-22 US disclosed
WO-2010030739-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-18 WO disclosed
WO-2010030730-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-18 WO disclosed
US-20100063135-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF ABBOTT LABORATORIES (US) 2010-03-11 US disclosed
EP-1061922-B9 USE OF N-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS UNITED THERAPEUTICS CORP (US) 2007-03-07 EP disclosed
EP-1061922-B1 USE OF N-SUBSTITUTED-1,5-DIDEOXY-1,5-IMINO-D-GLUCITOL COMPOUNDS FOR TREATING HEPATITIS VIRUS INFECTIONS SEARLE LLC (US) 2006-06-28 EP disclosed
EP-0141593-A2 Shampoo compositions THE PROCTER & GAMBLE COMPANY (US) 1985-05-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099738-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF LIPA, LIPG, LIPC TSHR 1020/4885ALDH1A1 1734/4885THRB 1606/4885
US-20100063135-A1 POLYETHYLENE GLYCOL LIPID CONJUGATES AND USES THEREOF LIPA, LIPG, LIPC TSHR 1020/4885ALDH1A1 1734/4885THRB 1606/4885
US-20190021998-A1 TOPICAL NANOEMULSION THERAPY FOR WOUNDS CUTA, MMP8, DSG1 TSHR 4850/4885ALDH1A1 2106/4885THRB 4831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.