Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 8/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 8/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933518 | 0.90 | CHRM1 (0.39) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL16933511 | 0.84 | CHRM5 (0.34) | CHRM1CHRM3CHRM5CHRM2OPRM1 | |
| SCHEMBL16934160 | 0.76 | CHRM5 (0.36) | CHRM1CHRM3CHRM5CHRM2OPRM1 | |
| SCHEMBL29399370 | 0.75 | NTMT1 (0.43) | CHRM1CHRM3CHRM5CHRM2POLB | |
| SCHEMBL16933504 | 0.73 | CHRM5 (0.40) | CHRM1CHRM3CHRM5CHRM2OPRM1 | |
| SCHEMBL15578074 | 0.72 | HSD11B1 (0.46) | HSD11B1TACR1CYP2D6CYP2C9LMNA | |
| Hydrochloric Acid SCHEMBL8963791 | 0.71 | CHRM3 (0.46) | CHRM1CHRM3CHRM5CHRM2LMNA | |
| SCHEMBL15578209 | 0.70 | CHRM5 (0.43) | CHRM1CHRM3CHRM5CHRM2 | |
| SCHEMBL12614662 | 0.70 | FASN (0.46) | CHRM5 | |
| SCHEMBL15578122 | 0.69 | POLB (0.48) | HSD11B1LMNAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150210681-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210681-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GBA1, GBA2, GAA | CHRM1 4870/4885CHRM3 4832/4885CHRM5 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.