Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 11/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 11/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 11/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16933613 | 0.94 | DGAT1 (0.33) | CHRM5CHRM1CHRM3FFAR4DGAT1 | |
| SCHEMBL16933598 | 0.90 | FFAR4 (0.36) | CHRM5CHRM1CHRM3CHRM2FFAR4 | |
| SCHEMBL16933687 | 0.85 | CHRM5 (0.42) | CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL16933601 | 0.84 | FFAR4 (0.35) | CHRM5CHRM1CHRM3FFAR4DGAT1 | |
| SCHEMBL16933481 | 0.80 | CHRM5 (0.40) | CHRM5CHRM1CHRM3 | |
| SCHEMBL16933479 | 0.80 | CHRM5 (0.40) | CHRM5CHRM1CHRM3 | |
| SCHEMBL16933472 | 0.79 | FFAR4 (0.36) | CHRM5CHRM1CHRM3CHRM2FFAR4 | |
| SCHEMBL16933480 | 0.78 | KCNH2 (0.43) | CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL29399430 | 0.77 | NTMT1 (0.49) | — | |
| SCHEMBL16933567 | 0.77 | CHRM5 (0.42) | CHRM5CHRM1CHRM3CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150210681-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GENZYME CORPORATION (US) | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210681-A1 | GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | GBA1, GBA2, GAA | CHRM5 4860/4885CHRM1 4870/4885CHRM3 4832/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.