Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 20/20 | 0.59 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22643005 | 0.75 | CTSC (0.50) | CTSC | |
| SCHEMBL22643031 | 0.75 | CTSC (0.50) | CTSC | |
| SCHEMBL22642937 | 0.75 | CTSC (0.50) | CTSC | |
| SCHEMBL22643174 | 0.75 | CTSC (0.50) | CTSC | |
| SCHEMBL19186779 | 0.75 | CTSC (0.50) | CTSC | |
| SCHEMBL19186938 | 0.74 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16052865 | 0.73 | CTSC (0.71) | CTSCCTSK | |
| SCHEMBL6387864 | 0.71 | ROCK2 (0.44) | CTSCCTSK | |
| SCHEMBL22643499 | 0.70 | CTSC (1.00) | CTSCCTSK | |
| SCHEMBL16064545 | 0.70 | CTSC (1.00) | CTSCCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3097086-A1 | (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE I INHIBITORS | Astrazeneca AB (SE) | 2016-11-30 | — | — | EP | disclosed |
| WO-2015110826-A1 | (2S)-N-[(1S)-1-CYANO-2-PHENYLETHYL]-1,4-OXAZEPANE-2-CARBOXAMIDES AS DIPEPTIDYL PEPTIDASE I INHIBITORS | ASTRAZENECA AB (SE) | 2015-07-30 | — | — | WO | disclosed |