Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | CNR1 | P21554 | 3/20 | 0.52 |
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | HLCS | P50747 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | PLCD1 | P51178 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
| ▸ | FGF1 | P05230 | 1/20 | 0.45 |
| ▸ | FGF2 | P09038 | 1/20 | 0.45 |
| ▸ | VEGFA | P15692 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13049573 | 1.00 | TDP1 (0.53) | TDP1CNR1CNR2HLCSF2 | |
| SCHEMBL3755939 | 0.89 | TDP1 (0.56) | TDP1CNR1CNR2F2PRSS1 | |
| SCHEMBL3755935 | 0.89 | TDP1 (0.56) | TDP1CNR1CNR2F2PRSS1 | |
| SCHEMBL13049453 | 0.86 | APEX1 (0.57) | TDP1CNR1CNR2HLCSF2 | |
| SCHEMBL16938361 | 0.86 | APEX1 (0.57) | TDP1CNR1CNR2HLCSF2 | |
| SCHEMBL13049629 | 0.83 | TDP1 (0.46) | TDP1CNR1CNR2 | |
| SCHEMBL16938351 | 0.83 | TDP1 (0.46) | TDP1CNR1CNR2 | |
| SCHEMBL12320610 | 0.82 | HLCS (0.71) | TDP1CNR1CNR2HLCSF2 | |
| SCHEMBL15870672 | 0.82 | HLCS (0.71) | TDP1CNR1CNR2HLCSF2 | |
| SCHEMBL22493325 | 0.82 | HLCS (0.71) | TDP1CNR1CNR2HLCSF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9089605-B2 | Quinone derivatives, pharmaceutical compositions, and uses thereof | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2015-07-28 | — | — | US | disclosed |