SCHEMBL16940896

SCHEMBL16940896

CC1(C)c2cc3c4ccccc4c4ccccc4c3cc2-c2cc3c4cc5c6ccccc6c6ccccc6c5cc4n(-c4ccc5c6ccccc6n(-c6ccccc6)c5c4)c3cc21

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.44
▸ ATM Q13315 1/20 0.44
▸ L3MBTL1 Q9Y468 1/20 0.44
▸ HDAC4 P56524 1/20 0.31
▸ MAPK8 P45983 1/20 0.31
▸ PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18062364 0.94 KDM4E (0.41) KDM4EATML3MBTL1PGR
SCHEMBL17071000 0.94 KDM4E (0.41) KDM4EATML3MBTL1PGR
SCHEMBL16076341 0.94 KDM4E (0.47) KDM4EATML3MBTL1HDAC4MAPK8
SCHEMBL16940903 0.93 KDM4E (0.46) KDM4EATML3MBTL1HDAC4MAPK8
SCHEMBL16076353 0.93 KDM4E (0.46) KDM4EATML3MBTL1HDAC4MAPK8
SCHEMBL18351605 0.92 KDM4E (0.51) KDM4EATML3MBTL1HDAC4MAPK8
SCHEMBL18351613 0.90 KDM4E (0.51) KDM4EATML3MBTL1HDAC4MAPK8
SCHEMBL16076436 0.90 KDM4E (0.40) KDM4EATML3MBTL1
SCHEMBL14822438 0.90 KDM4E (0.55) KDM4EATML3MBTL1HDAC4MAPK8
SCHEMBL18062348 0.90 KDM4E (0.41) KDM4EATML3MBTL1PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3042944-B1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE LUMINESCENCE TECH CORP (TW) 2017-05-10 — — EP disclosed
EP-3042944-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE Luminescence Technology Corp. (TW) 2016-07-13 — — EP disclosed
US-9190619-B2 Compound for organic electroluminescence device LUMINESCENCE TECHNOLOGY CORP (TW) 2015-11-17 — — US disclosed
US-9190619-B2 Compound for organic electroluminescence device LUMINESCENCE TECHNOLOGY CORP (TW) 2015-11-17 — — US disclosed
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP (TW) 2015-07-30 — — US disclosed
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP (TW) 2015-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLCO4C1, LEF1, SLCO2B1 KDM4E 2458/4885ATM 3958/4885L3MBTL1 1111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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