Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16076353 | 0.99 | KDM4E (0.46) | KDM4EATML3MBTL1HDAC4MAPK8 | |
| SCHEMBL16940903 | 0.96 | KDM4E (0.46) | KDM4EATML3MBTL1HDAC4MAPK8 | |
| SCHEMBL16076436 | 0.96 | KDM4E (0.40) | KDM4EATML3MBTL1MAPK1ALDH1A1 | |
| SCHEMBL14822604 | 0.95 | KDM4E (0.50) | KDM4EATML3MBTL1HDAC4MAPK8 | |
| SCHEMBL14822261 | 0.95 | KDM4E (0.50) | KDM4EATML3MBTL1HDAC4MAPK8 | |
| SCHEMBL16940896 | 0.94 | KDM4E (0.44) | KDM4EATML3MBTL1HDAC4MAPK8 | |
| SCHEMBL18351605 | 0.93 | KDM4E (0.51) | KDM4EATML3MBTL1HDAC4MAPK8 | |
| SCHEMBL14822438 | 0.93 | KDM4E (0.55) | KDM4EATML3MBTL1HDAC4MAPK8 | |
| SCHEMBL14886308 | 0.92 | KDM4E (0.37) | KDM4EATML3MBTL1 | |
| SCHEMBL802130 | 0.92 | KDM4E (0.56) | KDM4EATML3MBTL1HDAC4MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3120396-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2021-06-02 | — | — | EP | disclosed |
| WO-2021037401-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2021-03-04 | — | — | WO | disclosed |
| WO-2020127165-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-25 | — | — | WO | disclosed |
| US-9978957-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | disclosed |
| US-9978957-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2018-05-22 | — | — | US | disclosed |
| US-20170092875-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2017-03-30 | — | — | US | disclosed |
| US-20170092875-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2017-03-30 | — | — | US | disclosed |
| US-20170018722-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-20170018722-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-01-19 | — | — | US | disclosed |
| US-9515266-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-9515266-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-12-06 | — | — | US | disclosed |
| US-20140275530-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
| US-20140275530-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2014-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170018722-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | EFNA1, TTI1, TERT | KDM4E 2652/4885ATM 2760/4885L3MBTL1 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.