SCHEMBL16940930

SCHEMBL16940930

CC1(C)c2cc3c4ccccc4c4ccccc4c3cc2-c2cc3c4cc5c6ccccc6c6ccccc6c5cc4n(-c4nc(-c5ccccc5)cc(-c5ccccc5)n4)c3cc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.35
▸ L3MBTL1 Q9Y468 4/20 0.35
▸ KDM4E B2RXH2 4/20 0.35
▸ MAPK1 P28482 3/20 0.35
▸ NPSR1 Q6W5P4 2/20 0.35
▸ MEN1 O00255 7/20 0.33
▸ KMT2A Q03164 7/20 0.33
▸ TDP1 Q9NUW8 3/20 0.33
▸ TSHR P16473 2/20 0.33
▸ ATM Q13315 1/20 0.33
▸ HPGD P15428 6/20 0.32
▸ SMN1; SMN2 Q16637 4/20 0.32
▸ LMNA P02545 3/20 0.32
▸ ACACA Q13085 1/20 0.32
▸ ALDH1A1 P00352 5/20 0.32
▸ ADORA1 P30542 3/20 0.32
▸ ADORA2A P29274 2/20 0.32
▸ HTT P42858 1/20 0.32
▸ CYP1A2 P05177 1/20 0.32
▸ CYP2C9 P11712 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18062395 0.94 MAPT (0.33) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL17070999 0.91 MAPT (0.32) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL17380960 0.90 MAPT (0.36) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL17886453 0.86 KDM4E (0.37) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL783565 0.86 MAPT (0.34) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL23376410 0.86 L3MBTL1 (0.41) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL14886356 0.86 MAPT (0.31) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL18326874 0.85 TSHR (0.34) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL17921514 0.84 MEN1 (0.43) MAPTL3MBTL1KDM4EMAPK1NPSR1
SCHEMBL15801403 0.84 KDM4E (0.35) MAPTL3MBTL1KDM4EMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3042944-B1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE LUMINESCENCE TECH CORP (TW) 2017-05-10 — — EP disclosed
EP-3042944-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENT DEVICE Luminescence Technology Corp. (TW) 2016-07-13 — — EP disclosed
US-9190619-B2 Compound for organic electroluminescence device LUMINESCENCE TECHNOLOGY CORP (TW) 2015-11-17 — — US disclosed
US-9190619-B2 Compound for organic electroluminescence device LUMINESCENCE TECHNOLOGY CORP (TW) 2015-11-17 — — US disclosed
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP (TW) 2015-07-30 — — US disclosed
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP (TW) 2015-07-30 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLCO4C1, LEF1, SLCO2B1 MAPT 784/4885L3MBTL1 1111/4885KDM4E 2458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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