SCHEMBL169416

SCHEMBL169416

[CH2]c1ccccc1N(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.44
GAA P10253 4/20 0.44
ALDH1A1 P00352 4/20 0.44
TSHR P16473 3/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
KDM4E B2RXH2 2/20 0.44
CHEK1 O14757 1/20 0.43
NEK2 P51955 1/20 0.43
LIMK1 P53667 1/20 0.43
DYRK1A Q13627 1/20 0.43
CLK4 Q9HAZ1 1/20 0.43
HTR6 P50406 2/20 0.39
LMNA P02545 2/20 0.39
NSD2 O96028 1/20 0.39
EGFR P00533 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
EP300 Q09472 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27974730 0.97 MAPT (0.43) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL8734893 0.97 MAPT (0.43) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL29055174 0.97 MAPT (0.43) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL7946689 0.97 MAPT (0.43) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL2491630 0.80 MAPT (0.42) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL28875374 0.79 MAPT (0.37) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL65263 0.78 MAPT (0.55) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL816506 0.77 MAPT (0.44) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL815705 0.77 MAPT (0.44) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL2092236 0.75 EGFR (0.38) ALDH1A1SMN1; SMN2LMNAEGFRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1574 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024066457-A1 RARE EARTH METAL CATALYST COMPOSITION, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国石油天然气股份有限公司 2024-04-04 WO claimed
CN-114315689-B Disulfanylphthalimide compound, preparation method and application thereof 四川大学 2023-04-07 CN claimed
CN-110418807-B Method for producing polar olefin polymer and copolymer 国立研究开发法人理化学研究所 2023-01-17 CN claimed
CN-114716386-A Novel exosome inhibitor and preparation method thereof 北京和理咨询有限公司 2022-07-08 CN claimed
CN-114315689-A Disulfanylphthalimide compound, preparation method and application thereof 四川大学 2022-04-12 CN claimed
CN-110483531-A A kind of water-soluble porphyrin ene derivative, preparation method, anti-tumor drug and application LI DEFANG 2019-11-22 CN claimed
US-20190308179-A1 CHROME COMPOUND, CATALYST SYSTEM USING SAME, AND METHOD FOR PREPARING ETHYLENE OLIGOMER AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION (KR) 2019-10-10 US claimed
EP-3536696-A1 CHROME COMPOUND, CATALYST SYSTEM USING SAME, AND METHOD FOR PREPARING ETHYLENE OLIGOMER Ajou University Industry-Academic Cooperation Foundation (KR) 2019-09-11 EP claimed
EP-3363788-A1 CANNABINOID RECEPTOR MODULATORS Arena Pharmaceuticals, Inc. (US) 2018-08-22 EP claimed
CN-105326809-B One kind containing CaCO3The preparation method of the composite natral high molecule microcapsule of particle 武汉理工大学 2018-08-07 CN claimed
EP-0656075-A1 ELECTROCHEMICAL PREPARATION OF ADDITION POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY (US) 1995-06-07 EP claimed
EP-0632819-A1 ADDITION POLYMERIZATION CATALYSTS COMPRISING REDUCED OXIDATION STATE METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1995-01-11 EP claimed
WO-1995000683-A1 ELECTROCHEMICAL PREPARATION OF ADDITION POLYMERIZATION CATALYSTS THE DOW CHEMICAL COMPANY (US) 1995-01-05 WO claimed
US-5374696-A Catalyzing the addition polymerization in presence of titanium metal complexes with cocatalysts THE DOW CHEMICAL COMPANY (US) 1994-12-20 US claimed
US-5322844-A Cardiovascular disorders, antiinflammatory agents, antiallergens GODECKE AKTIENGESELLSCHAFT (DE) 1994-06-21 US claimed
WO-1993019104-A1 ADDITION POLYMERIZATION CATALYSTS COMPRISING REDUCED OXIDATION STATE METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 1993-09-30 WO claimed
US-5185352-A Treating or preventing cardiovascular disorders GOEDECKE AKTIENGESELLSCHAFT (DE) 1993-02-09 US claimed
US-4976889-A 4-formylaminopiperidine derivatives, their use as stabilizers and organic material stabilized with the said derivatives BASF AKTIENGESELLSCHAFT (DE) 1990-12-11 US claimed
EP-0041590-B1 CHEMICAL INDICATOR REAGENT FOR THE IN VITRO DETECTION OF PREGNANCY La Société Anstalt, dite FARMATEST (LI) 1985-02-20 EP claimed
US-3993643-A ANTISCHISTOSOMAL STANFORD RESEARCH INSTITUTE (US) 1976-11-23 US claimed