SCHEMBL7946689

SCHEMBL7946689

[CH2]c1ccccc1N(C)C.[Zr]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.43
GAA P10253 4/20 0.43
ALDH1A1 P00352 4/20 0.43
TSHR P16473 3/20 0.43
SMN1; SMN2 Q16637 2/20 0.43
TP53 P04637 1/20 0.43
KDM4E B2RXH2 2/20 0.42
CHEK1 O14757 1/20 0.41
NEK2 P51955 1/20 0.41
LIMK1 P53667 1/20 0.41
DYRK1A Q13627 1/20 0.41
CLK4 Q9HAZ1 1/20 0.41
HTR6 P50406 2/20 0.38
LMNA P02545 2/20 0.38
NSD2 O96028 1/20 0.38
EGFR P00533 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
EP300 Q09472 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169416 0.97 MAPT (0.44) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL8734893 0.95 MAPT (0.43) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL27974730 0.95 MAPT (0.43) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL29055174 0.95 MAPT (0.43) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL2491630 0.78 MAPT (0.42) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL28875374 0.77 MAPT (0.37) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL65263 0.76 MAPT (0.55) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL815705 0.75 MAPT (0.44) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL816506 0.75 MAPT (0.44) MAPTGAAALDH1A1TSHRSMN1; SMN2
SCHEMBL2092236 0.73 EGFR (0.38) ALDH1A1SMN1; SMN2LMNAEGFRMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115260366-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-11-01 CN disclosed
CN-110603274-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-09-30 CN disclosed
CN-110612315-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-26 CN disclosed
CN-110582518-B Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2022-08-09 CN disclosed
CN-108026115-B Multi-head or double-head composition capable of being used for chain shuttling and preparation method thereof 陶氏环球技术有限责任公司 2021-11-09 CN disclosed
CN-110612315-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-24 CN disclosed
CN-110603271-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-20 CN disclosed
CN-110603274-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-20 CN disclosed
CN-110582518-A Catalyst system for forming multi-block copolymers 陶氏环球技术有限责任公司 2019-12-17 CN disclosed
CN-110546171-A catalyst system for forming multi-block copolymers DOW GLOBAL TECHNOLOGIES LLC 2019-12-06 CN disclosed
CN-1120849-C Highly soluble olefin polymerization catalyst activators DOW GLOBAL TECHNOLOGY CO (US) 2003-09-10 CN disclosed
CN-1334845-A Hot melt adhesive polypropylene/ethylene polymer fibers and compositions for making the same DOW CHEMICAL CO (US) 2002-02-06 CN disclosed
WO-2001046201-A1 GALLIUM OR INDIUM-BRIDGED GROUP 4 METAL COMPLEXES THE DOW CHEMICAL COMPANY (US) 2001-06-28 WO disclosed
CN-1216548-A Yttrium-containing metal complexes and olefin polymerization process DOW CHEMICAL CO (US) 1999-05-12 CN disclosed
CN-1214699-A Highly soluble olefin polymerization catalyst activator DOW CHEMICAL CO (US) 1999-04-21 CN disclosed
CN-1214698-A Solution polymerization process with dispersed catalyst activator DOW CHEMICAL CO (US) 1999-04-21 CN disclosed