SCHEMBL169448

SCHEMBL169448

CCCCCc1ncnc(O)n1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.38
CYP3A4 P08684 2/20 0.38
PI4KA P42356 1/20 0.37
PI4K2B Q8TCG2 1/20 0.37
PI4K2A Q9BTU6 1/20 0.37
PI4KB Q9UBF8 1/20 0.37
ESR1 P03372 2/20 0.37
ADRA2A P08913 2/20 0.37
ADORA3 P0DMS8 2/20 0.37
TACR2 P21452 2/20 0.37
SLC6A2 P23975 2/20 0.37
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
SHBG P04278 1/20 0.37
TP53 P04637 1/20 0.37
HSPD1 P10809 1/20 0.37
ADRB3 P13945 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4591162 0.86 KCNH2 (0.43) PTGS2CYP3A4PI4KAPI4K2BPI4K2A
SCHEMBL2793062 0.84 KCNH2 (0.47) PTGS2CYP3A4PI4KAPI4K2BPI4K2A
Ammonia Solution, Strong SCHEMBL29135408 0.82 KCNH2 (0.45) PTGS2CYP3A4PI4KAPI4K2BPI4K2A
Serine SCHEMBL4565759 0.82 SPHK1 (0.41)
SCHEMBL7203347 0.79 PI4KA (0.36) CYP3A4PI4KAPI4K2BPI4K2API4KB
SCHEMBL1542351 0.78 KCNH2 (0.42) PTGS2CYP3A4PI4KAPI4K2BPI4K2A
Resorcinol SCHEMBL4055637 0.78 PTGS2 (0.44) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL8039222 0.77 PTGS2 (0.40) PTGS2CYP3A4ESR1ADRA2AADORA3
SCHEMBL16784008 0.77
SCHEMBL29168795 0.77 PTGS2 (0.40) PTGS2CYP3A4ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3078698-B1 POLYARYLENE POLYMERS ROHM & HAAS ELECT MAT (US) 2019-11-20 EP claimed
EP-3078698-A1 POLYARYLENE POLYMERS Rohm and Haas Electronic Materials LLC (US) 2016-10-12 EP claimed
US-20160289493-A1 POLYARYLENE POLYMERS U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2016-10-06 US claimed
US-8383088-B2 Coumestan-like antioxidants and UV absorbants BASF SE (DE) 2013-02-26 US claimed
EP-2121141-B1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS BASF SE (DE) 2012-02-15 EP claimed
US-20100330009-A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS CIBA CORPORATION (US) 2010-12-30 US claimed
CN-1902279-B Aldehyde inhibitor composition and polyacetal resin composition POLYPLASTICS CO 2010-11-24 CN claimed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US claimed
EP-2121141-A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS BASF SE (DE) 2009-11-25 EP claimed
US-20090143506-A1 Aldehyde inhibitor composition and polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-06-04 US claimed
EP-0697481-A2 Aqueous textile treatment compositions containing an ultra-violet absorbing agent CIBA-GEIGY AG (CH) 1996-02-21 EP claimed
EP-0682145-A2 Textile treatment CIBA-GEIGY AG (CH) 1995-11-15 EP claimed
US-5436349-A Photostabilizers for polymers for radiation resistance CIBA-GEIGY CORPORATION (US) 1995-07-25 US claimed
EP-0659877-A2 Composition for the treatment of textiles CIBA-GEIGY AG (CH) 1995-06-28 EP claimed
EP-0576527-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1994-01-05 EP claimed
EP-0572554-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS Ciba SC Holding AG (CH) 1993-12-08 EP claimed
US-5208012-A Phenolic triazine DAIKYO GOMU SEIKO LTD. (JP) 1993-05-04 US claimed
EP-0525262-A1 Anti-inflammatory cosmetic composition DAIKYO GOMU SEIKO LTD. (JP) 1993-02-03 EP claimed
WO-1992014717-A1 5-SULFONYL-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO claimed
WO-1992014718-A1 5-THIO-SUBSTITUTED BENZOTRIAZOLE UV-ABSORBERS AND STABILIZED COMPOSITIONS CIBA-GEIGY AG (CH) 1992-09-03 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100330009-A1 COUMESTAN-LIKE ANTIOXIDANTS AND UV ABSORBANTS TYR, NQO1, SIRT3 PTGS2 1477/4885CYP3A4 61/4885PI4KA 3748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.