Serine

Serine

SCHEMBL4565759

CCCCCc1ncnc(O)n1.N[C@@H](CO)C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 11/20 0.41
GRIK1 P39086 3/20 0.35
GRIK2 Q13002 2/20 0.35
SLC1A2 P43004 2/20 0.35
SLC1A1 P43005 2/20 0.35
SPHK2 Q9NRA0 1/20 0.35
CYP1A2 P05177 1/20 0.35
RECQL P46063 1/20 0.35
SLC1A3 P43003 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL169448 0.82 PTGS2 (0.38)
Serine SCHEMBL4565758 0.71 SPHK1 (0.35) SPHK1SLC1A1SPHK2
SCHEMBL4591162 0.70 KCNH2 (0.43)
Serine SCHEMBL3239891 0.69 SLC1A5 (0.43) SLC1A2SLC1A1SLC1A3
Serine SCHEMBL28414044 0.69 SLC1A1 (0.49) SPHK1GRIK1GRIK2SLC1A2SLC1A1
Serine SCHEMBL9988701 0.68 BID (0.55) SPHK1
Cetostearyl Alcohol SCHEMBL27937331 0.67 GRIK1 (0.53) SPHK1GRIK1GRIK2SLC1A2SLC1A1
Dodecanol SCHEMBL30392850 0.67 GRIK1 (0.53) SPHK1GRIK1GRIK2SLC1A2SLC1A1
Ammonia Solution, Strong SCHEMBL29135408 0.67 KCNH2 (0.45)
Butylbenzyl SCHEMBL28121146 0.66 KIF11 (0.58) SPHK1GRIK1SLC1A2SLC1A1SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1674526-B9 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2013-05-29 EP claimed
EP-1674526-B1 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-12-05 EP claimed
EP-1679346-B1 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-11-14 EP claimed
US-20070123617-A1 Polyacetal resin composition DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT 2007-05-31 US claimed
US-20070032605-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-02-08 US claimed
EP-1679346-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-07-12 EP claimed
EP-1674526-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-06-28 EP claimed
EP-1674526-B9 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2013-05-29 EP disclosed
EP-1674526-B1 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-12-05 EP disclosed
EP-1679346-B1 POLYACETAL RESIN COMPOSITION POLYPLASTICS CO (JP) 2012-11-14 EP disclosed
US-7638565-B2 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2009-12-29 US disclosed
US-20070123617-A1 Polyacetal resin composition DEUTSCHE BANK AG, NEW YORK BRANCH, AS COLLATERAL AGENT 2007-05-31 US disclosed
US-20070054998-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-03-08 US disclosed
US-20070032605-A1 Polyacetal resin composition POLYPLASTICS CO., LTD. (JP) 2007-02-08 US disclosed
EP-1686156-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-08-02 EP disclosed
EP-1679346-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-07-12 EP disclosed
EP-1674526-A1 POLYACETAL RESIN COMPOSITION Polyplastics Co., Ltd. (JP) 2006-06-28 EP disclosed