⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28200979 | 0.78 | — | — | |
| SCHEMBL7314602 | 0.76 | ALPL (0.36) | — | |
| SCHEMBL7076085 | 0.76 | — | — | |
| SCHEMBL28017232 | 0.69 | — | — | |
| SCHEMBL4328730 | 0.67 | — | — | |
| SCHEMBL18622046 | 0.67 | — | — | |
| SCHEMBL5839039 | 0.65 | — | — | |
| SCHEMBL17682032 | 0.65 | — | — | |
| SCHEMBL28017088 | 0.62 | KDM4E (0.30) | — | |
| SCHEMBL18881105 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112457203-B | Preparation method of 2-amino-2-methyl-1-propanol | 苏州亚科科技股份有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-112457203-A | Preparation method of 2-amino-2-methyl-1-propanol | 苏州亚科科技股份有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-112457203-B | Preparation method of 2-amino-2-methyl-1-propanol | 苏州亚科科技股份有限公司 | 2022-08-16 | — | — | CN | disclosed |
| CN-112457203-A | Preparation method of 2-amino-2-methyl-1-propanol | 苏州亚科科技股份有限公司 | 2021-03-09 | — | — | CN | disclosed |
| US-10478426-B2 | Enhancer of Zeste Homolog 2 inhibitors | GLAXOSMITHKLINE LLC (US) | 2019-11-19 | — | — | US | disclosed |
| US-20180207144-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | GLAXOSMITHKLINE LLC | 2018-07-26 | — | — | US | disclosed |
| US-9956210-B2 | Enhancer of zeste homolog 2 inhibitors | GLAXOSMITHKLINE LLC (US) | 2018-05-01 | — | — | US | disclosed |
| EP-3246027-A1 | INDOLE DERIVATIVES FOR THE TREATMENT OF CANCER | GlaxoSmithKline LLC (US) | 2017-11-22 | — | — | EP | disclosed |
| US-9649307-B2 | Indoles | GLAXOSMITHKLINE LLC (US) | 2017-05-16 | — | — | US | disclosed |
| US-20170095461-A1 | ENHANCER OF ZESTE HOMOLOG 2 INHIBITORS | GLAXOSMITHKLINE LLC | 2017-04-06 | — | — | US | disclosed |
| EP-2755962-B1 | AZAINDAZOLES | GLAXOSMITHKLINE LLC (US) | 2017-03-01 | — | — | EP | disclosed |
| US-20130059849-A1 | AZAINDAZOLES | GLAXOSMITHKLINE LLC | 2013-03-07 | — | — | US | disclosed |
| US-20130053397-A1 | INDOLES | GLAXOSMITHKLINE LLC | 2013-02-28 | — | — | US | disclosed |
| WO-2012075080-A1 | INDOLES | GLAXOSMITHKLINE LLC (US) | 2012-06-07 | — | — | WO | disclosed |
| WO-2012005805-A1 | AZAINDAZOLES | GLAXOSMITHKLINE LLC (US) | 2012-01-12 | — | — | WO | disclosed |
| WO-2011140324-A1 | INDOLES | GLAXOSMITHKLINE LLC (US) | 2011-11-10 | — | — | WO | disclosed |
| WO-2010019204-A1 | ANTIFUNGAL AGENTS | MERCK SHARP & DOHME CORP. (US) | 2010-02-18 | — | — | WO | disclosed |
| US-20090156807-A1 | Anti-tumor Compounds Derived From 1,4,5,8-tetrachloroanthraquinone | ISHMAEL D RICHARD | 2009-06-18 | — | — | US | disclosed |
| EP-1242495-A1 | BLOCKED POLYISOCYANATES CONTAINING PHENOLIC GROUPS | Bayer Corporation (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001044341-A1 | BLOCKED POLYISOCYANATES CONTAINING PHENOLIC GROUPS | BAYER CORPORATION (US) | 2001-06-21 | — | — | WO | disclosed |