Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1252986 | 0.97 | KDM4E (0.52) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL5933553 | 0.92 | KDM4E (0.48) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL5932801 | 0.92 | KDM4E (0.48) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL5932186 | 0.92 | KDM4E (0.48) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL13520201 | 0.90 | KDM4E (0.47) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL20710373 | 0.89 | ALDH1A1 (0.48) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL16948551 | 0.87 | KDM4E (0.46) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL30284827 | 0.87 | TSHR (0.48) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL5933472 | 0.86 | ALDH1A1 (0.46) | KDM4EPOLBTDP1THRBALDH1A1 | |
| SCHEMBL4236221 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9757463-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2017-09-12 | — | — | US | disclosed |
| US-9745419-B2 | Aqueous polyglycidol synthesis with ultra-low branching | VANDERBILT UNIVERSITY (US) | 2017-08-29 | — | — | US | disclosed |
| US-20160206743-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | VANDERBILT UNIVERSITY | 2016-07-21 | — | — | US | disclosed |
| US-9161983-B2 | Linear polyester and semi-linear glycidol polymer systems: formulation and synthesis of novel monomers and macromolecular structures | VANDERBILT UNIVERSITY (US) | 2015-10-20 | — | — | US | disclosed |
| US-20150210805-A1 | AQUEOUS POLYGLYCIDOL SYNTHESIS WITH ULTRA-LOW BRANCHING | VANDERBILT UNIVERSITY | 2015-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160206743-A1 | Linear Polyester and Semi-Linear Glycidol Polymer Systems: Formulation and Synthesis of Novel Monomers and Macromolecular Structures | STT3A, STT3B, B3GAT3 | KDM4E 3069/4885POLB 3126/4885TDP1 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.