Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.41 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.41 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 4/20 | 0.39 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.39 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30022409 | 0.84 | GABRP (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30103578 | 0.83 | GABRP (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30021638 | 0.82 | KIF11 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL1495149 | 0.82 | PARP14 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30333067 | 0.82 | PARP14 (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30021066 | 0.81 | KIF11 (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30103785 | 0.81 | CDK4 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30103660 | 0.80 | KIF11 (0.48) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30332625 | 0.79 | CDK4 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30332318 | 0.78 | GABRP (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9698352-B2 | Amine compound and use thereof | TOSOH CORPORATION (JP) | 2017-07-04 | — | — | US | disclosed |
| EP-2902391-B1 | NOVEL AMINE COMPOUND AND USE THEREOF | TOSOH CORP (JP) | 2017-03-08 | — | — | EP | disclosed |
| US-20150243901-A1 | NOVEL AMINE COMPOUND AND USE THEREOF | TOSOH CORPORATION (JP) | 2015-08-27 | — | — | US | disclosed |
| EP-2902391-A1 | NOVEL AMINE COMPOUND AND USE THEREOF | Tosoh Corporation (JP) | 2015-08-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150243901-A1 | NOVEL AMINE COMPOUND AND USE THEREOF | DRD1, MLLT1, DRD4 | GABRP 4743/4885GABRD 4167/4885GABRA1 4270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.