Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
| ▸ | KLRK1 | P26718 | 1/20 | 0.30 |
| ▸ | MICA | Q29983 | 1/20 | 0.30 |
| ▸ | RAET1L | Q5VY80 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16957736 | 0.93 | HDAC4 (0.40) | HTR2CHDAC4HDAC2HDAC8KMO | |
| SCHEMBL16961241 | 0.93 | HDAC4 (0.44) | HTR2CHDAC4HDAC2HDAC8KMO | |
| SCHEMBL16959967 | 0.82 | — | — | |
| SCHEMBL16961065 | 0.79 | HTR2C (0.41) | HTR2CHDAC4HDAC2HDAC8KMO | |
| SCHEMBL16959998 | 0.76 | HDAC4 (0.38) | HTR2CHDAC4HDAC2HDAC8KMO | |
| SCHEMBL16956298 | 0.76 | HTR2C (0.36) | HTR2CHDAC4HDAC2HDAC8KMO | |
| SCHEMBL15566600 | 0.75 | HTR2C (0.43) | HTR2CHDAC4HDAC2HDAC8KMO | |
| SCHEMBL6935362 | 0.74 | HTR2C (0.52) | HTR2CHDAC4HDAC2HDAC8KMO | |
| SCHEMBL16961088 | 0.73 | HTR2C (0.32) | HTR2C | |
| SCHEMBL16957285 | 0.73 | HDAC4 (0.45) | HTR2CHDAC4HDAC2HDAC8KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900645-A1 | 3-PHENYLISOXAZOLIN DERIVATIVES WITH HERBICIDAL ACTION | Bayer CropScience AG (DE) | 2015-08-05 | — | — | EP | disclosed |